Demographics contains subject identity, enrollment, study participation, longitudinal episode structure, survival status, family and medical history, and other contextual information needed to interpret records across the model.
SubjectCharacteristics
SubjectCharacteristics captures core subject-level identifiers, data source context, and last-known survival/contact status needed to anchor all other records in the model.
Slot
Description
Range
honest_broker_subject_id
string
data_contributor_id
data_source
last_known_survival_status
age_last_contact
decimal
age_last_contact_unit
age_last_contact_precision
Timing
Timing represents named clinical or research timepoints and their associated ages, providing the longitudinal structure used to align observations across the model.
Slot
Description
Range
honest_broker_subject_id
string
subject_characteristics
SubjectCharacteristics
timepoint
timing_age_at
integer
age_unit
age_precision
FamilyMedicalHistory
FamilyMedicalHistory captures diabetes-related conditions reported among relatives, supporting representation of inherited patterns and familial disease context.
Slot
Description
Range
honest_broker_subject_id
string
subject_characteristics
SubjectCharacteristics
relation_honest_broker_subject_id
string
relation
condition
source
Demographics
Demographics captures subject-level sex, race, and ethnicity information used to describe study populations and support cohort characterization.
Slot
Description
Range
honest_broker_subject_id
string
subject_characteristics
SubjectCharacteristics
sex
ethnicity
race
MedicalHistory
MedicalHistory records prior or co-occurring medical conditions for a subject, including coded condition details when available.
Slot
Description
Range
honest_broker_subject_id
string
subject_characteristics
SubjectCharacteristics
age_at
integer
age_unit
age_precision
medical_history_condition
condition_other
string
condition_code
string
code_system
Testing
Testing contains laboratory, pathology, genomic, functional, anthropometric, and specimen-related observations used to characterize subjects, disease biology, eligibility, monitoring, and research sample availability.
Biometrics
Biometrics captures anthropometric measurements such as height, weight, BMI, and related standardized scores used to characterize growth and body size over time.
Slot
Description
Range
honest_broker_subject_id
string
subject_characteristics
SubjectCharacteristics
age_at
integer
age_unit
age_precision
measurement_type
measurement_numeric
decimal
measurement_unit
z_score
decimal
Biospecimen
Biospecimen records available subject specimens by sample type, supporting linkage between clinical data and biological materials for research use.
Slot
Description
Range
honest_broker_subject_id
string
subject_characteristics
SubjectCharacteristics
sample_type
GeneticAnalysis
GeneticAnalysis captures genetic testing results, including methods, genes, alteration details, HGVS nomenclature, reported significance, allelic state, and related external references.
Slot
Description
Range
honest_broker_subject_id
string
subject_characteristics
SubjectCharacteristics
age_at
integer
age_unit
age_precision
causative_alteration
status
genetic_analysis_sample_type
laboratory_name
cytogenetic_location
string
method
gene
alteration_type
alteration_effect
alteration_region
hgvs_accession
string
hgvs_coding
string
hgvs_protein
string
hgvs_genomic
string
iscn
string
reported_significance
allelic_state
maf_numeric
decimal
mosaicism
external_ref_id
string
external_ref_id_system
Testing
Testing captures laboratory, glucose-monitoring, and related clinical test results, including numeric values, units, interpretation, fasting status, and timepoint-specific testing context.
Slot
Description
Range
honest_broker_subject_id
string
subject_characteristics
SubjectCharacteristics
age_at
integer
age_unit
age_precision
test_type
testing_method
testing_measurement_type
result_modifier
string
result_numeric
string
result_unit
reference_range
string
result_interpretation
fasting_status
post_glucose_timepoint
string
post_glucose_timepoint_unit
Disease Attributes
Disease Attributes contains diagnostic, staging, anatomic, histologic, biologic, risk, extent-of-disease, and disease-site concepts used to characterize the subject's cancer or cancer-related condition.
DiseaseCharacteristics
DiseaseCharacteristics records monogenic diabetes-related disease features, including diabetes status, hypoglycemia, ketoacidosis, glucose range metrics, diet, and exercise observations.
Slot
Description
Range
honest_broker_subject_id
string
subject_characteristics
SubjectCharacteristics
age_at
integer
age_unit
age_precision
diabetes_status
hypoglycemia_frequency
severe_hypoglycemia_frequency
dka
time_in_range
decimal
cgm_range
diet
exercise
Intervention
Intervention contains treatment and procedure records, including surgery, medications, radiation therapy, transplantation, transfusion, cellular therapy, locoregional therapy, fertility preservation procedures, and protocol treatment modifications.
Treatment
Treatment captures diabetes-related medications and therapies, including medication class, name, dose, unit, route, frequency, timing, and reason for stopping treatment.
Slot
Description
Range
honest_broker_subject_id
string
subject_characteristics
SubjectCharacteristics
age_at_start
integer
age_at_stop
integer
age_unit
age_precision
reason_stop
dm_medication_class
medication_class_other
medication_name
string
medication_code
string
medication_concentration
medication_dose
decimal
medication_unit
frequency
route
AgeLastContactPrecisionEnum
Permissible Value
Description
Meaning
Approximate
Exact
AgeLastContactUnitEnum
Permissible Value
Description
Meaning
Years
Months
Weeks
Days
AllelicStateEnum
Permissible Value
Description
Meaning
Homozygous
Heterozygous
Compound Heterozygous
Unknown
Not Reported
AlterationEffectEnum
Permissible Value
Description
Meaning
Frameshift
Missense
Stop Gain (Nonsense)
None (Inframe)
AlterationRegionEnum
Permissible Value
Description
Meaning
Splice Site
5' UTR
3' UTR
AlterationTypeEnum
Permissible Value
Description
Meaning
Chromosome Arm Gain
Chromosome Arm Loss
Substitution
Deletion
Insertion
Indel
Duplication
Unknown
Not Reported
CGMRangeEnum
Permissible Value
Description
Meaning
Standard
Non-Standard
CodeSystemEnum
Permissible Value
Description
Meaning
CTCAE
ICD-9
ICD-10
SNOMED-CT
ConditionEnum
Permissible Value
Description
Meaning
Prediabetes
Type 1 Diabetes
Type 2 Diabetes
Monogenic Diabetes
Gestational Diabetes
Diabetes, NOS
DKAEnum
Permissible Value
Description
Meaning
Yes - Hyperglycermic DKA
Yes - Euglycemic DKA
No
DMMedicationClassEnum
Permissible Value
Description
Meaning
Insulin, Rapid-Acting
Insulin, Long-Acting
Insulin, Intermediate-Acting
Insulin, Combination
Insulin, NOS
Biguanide
Sulfonylurea
Meglitinide
Thiazolidinedione
Dipeptidylpeptidase 4 Inhibitor
Sodium-Glucose Co-Transporter 2 Inhibitor
GLP-1 Receptor Agonist
Dual GLP-1/GIP Receptor Agonist
Amylin Analog
Alpha-Glucosidase Inhibitor
Bile Acid-Binding Resin
DataContributorIDEnum
Permissible Value
Description
Meaning
UChicago Monogenic Diabetes Research Group
Barbara Davis Center / UColorado
Baylor
Boston Children's
Cincinnati Children's Hospital
Indiana
MGH
Maryland
Michigan
Nebraska
NorthShore
WashU
DataSourceEnum
Permissible Value
Description
Meaning
Self-Reported
EHR
DiabetesStatusEnum
Permissible Value
Description
Meaning
Yes
No
EthnicityEnum
Permissible Value
Description
Meaning
Hispanic or Latino
Not Hispanic or Latino
Unknown
Not Reported
ExternalRefIDSystemEnum
Permissible Value
Description
Meaning
ClinGen
ClinVar
FastingStatusEnum
Permissible Value
Description
Meaning
Fasting
Non-Fasting
Random
FrequencyEnum
Permissible Value
Description
Meaning
Once per day
Two times a day
Three times a day
Four times a day
As needed
Before every meal
Before meals and at bedtime
Every night at bedtime
Every week
GeneEnum
Permissible Value
Description
Meaning
6q24-Related Abnormalities
ABCC8
CEL
CFTR
DCAF17
EIF2AK3
FOXP3
GATA4
GATA6
GCK
GLIS3
HNF1A
HNF1B
HNF4A
IAPP (Amylin)
IER3IP1
IGF2/Russell Silver Syndrome
IL2RA
INS
INSR
KCNJ11
LRBA
mtDNA
NEUROD1
PAX4
PCBD1
PDX1 (IPF1)
PTF1A
RFX6
STAT3
WFS1
Unknown
Not Reported
GeneticAnalysisSampleTypeEnum
Permissible Value
Description
Meaning
Saliva
Blood
Buccal
Urine
Unknown
Not Reported
HypoglycemiaFrequencyEnum
Permissible Value
Description
Meaning
Once or twice in past year
Every few months
Once or twice a month
Once or twice a week
Daily or every other day
Never
LaboratoryNameEnum
Permissible Value
Description
Meaning
Ambry Genetics
Athena
Baylor Genetics
Blueprint
GeneDx
Invitae
LMG
Research Lab
Seattle Children's Hospital
UCGSL
Unknown
Not Reported
LastKnownSurvivalStatusEnum
Permissible Value
Description
Meaning
Alive
Dead
Unknown
Not Reported
MeasurementTypeEnum
Permissible Value
Description
Meaning
Height/Length
Weight
BMI
Raw BMI
MeasurementUnitEnum
Permissible Value
Description
Meaning
kg
cm
kg/m^2
percentile
(md_v1.3) ConsortiumNote: Use percentile as a unit when reporting pediatric BMI.
MedicalHistoryConditionEnum
Permissible Value
Description
Meaning
Abnormal Kidney Shape, Size, Or Number
Absent Or Missing Pancreas
Behavioral Difficulties
Congenital Heart Defect
Coronary Artery Disease
Difficulty With Social Interactions
Elevated Liver Enzymes / Lfts
Fatty Liver
Genitourinary Developmental Malformation Or Abnormality
Gestational Diabetes
Hepatomegaly
High Cholesterol, NOS
High Frequency Hearing Loss
High LDL
High Total Cholesterol
High Triglycerides
Hypertension
Hypoglycemia In Infancy
Intrauterine Growth Restriction
Liver Adenoma
Low Frequency Hearing Loss
Low LDL
Macroglossia
Nephropathy
Peripheral Artery Disease
Peripheral Neuropathy
Polycystic Kidney Diseasea
Proteinuria
Renal CystL
Retinopathy
Small For Gestational Age
Small Pancreas
Stroke
Umbilical Hernia
Other
(md_v1.3) ConsortiumNote: Only select 'Other' if the condition is not related to the provided list (which are designated as 'of interest' by the PREDICT group).