PCDC Data Model `1.15`

Schema IDhttps://models.d4cg.org/pcdc

LicenseCC BY-NC 4.0

Concepts37 classes · 328 slots · 177 enums

Community ·

View

Scope Matrix

Class Inclusion by View

Domain	Class	AML	GCT	HL	NBL	NRSTS	RMS
Demographics	ExternalReference
Demographics	FamilyMedicalHistory
Demographics	MedicalHistory
Demographics	OffProtocolTherapyStudy
Demographics	Person
Demographics	Study
Demographics	Subject
Demographics	SurvivalCharacteristic
Demographics	Timing
Disease Attributes	DiseaseCharacteristic
Disease Attributes	Histology
Disease Attributes	LesionCharacteristic
Disease Attributes	MyeloidSarcomaInvolvement
Disease Attributes	Staging
Disease Attributes	TumorAssessment
Intervention	BiopsySurgicalProcedure
Intervention	CellularImmunotherapy
Intervention	NonProtocolTherapy
Intervention	ProtocolTreatmentModifications
Intervention	RadiationTherapy
Intervention	StemCellTransplant
Intervention	TotalDose
Intervention	TransfusionMedicineProcedure
Monitoring	AdverseEvent
Monitoring	GrowingTeratomaSyndrome
Monitoring	LateEffects
Monitoring	MinimalResidualDisease
Monitoring	SecondaryMalignantNeoplasm
Monitoring	SubjectResponse
Testing	Biospecimen
Testing	Cytology
Testing	FunctionTest
Testing	Imaging
Testing	Immunohistochemistry
Testing	Lab
Testing	MolecularAnalysis
Testing	Vital

Rendered Raw

Demographics

Demographics contains subject identity, enrollment, study participation, longitudinal episode structure, survival status, family and medical history, and other contextual information needed to interpret records across the model.

Person

A person record captures individual-level demographic characteristics associated with a study subject, including sex, race, and ethnicity.

Diagram

Slot	Description	Range
submitter_id		`string`
subjects_submitter_id		`Subject`
sex
race
ethnicity

Subject

A subject record represents the core participant-level entity in the model and contains identifiers, consortium participation, contributor information, and high-level follow-up status.

Slot	Description	Range
consortium
submitter_id		`string`
honest_broker_subject_id		`string`
data_contributor_id
age_at_censor_status		`integer`
censor_status

ExternalReference

An external reference record links a subject to identifiers, resources, or URLs maintained outside the PCDC model.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
external_links		`string`
external_resource_icon_path		`string`
external_resource_id		`string`
external_resource_name		`string`
external_subject_id		`string`
external_subject_submitter_id		`string`
external_subject_url		`string`

Study

A study record describes a subject’s enrollment or participation in a study, protocol, treatment arm, or related research context.

Diagram

Slot	Description	Range
submitter_id		`string`
subjects_submitter_id		`Subject`
age_at_enrollment		`integer`
enrolled_status
study_id
treatment_arm
year_at_enrollment		`integer`
study_phase
study_type

Timing

A timing record provides reusable temporal anchors for disease phases, courses, cycles, and other time-dependent observations.

Diagram

Slot	Description	Range
submitter_id		`string`
subjects_submitter_id		`Subject`
timing_type
disease_phase
disease_phase_number		`integer`
age_at_disease_phase		`integer`
year_at_disease_phase		`integer`
course
course_number		`integer`
age_at_course_start		`integer`
age_at_course_end		`integer`
age_at_course_anc_500		`integer`
cycle_number		`integer`
age_at_cycle_start		`integer`
age_at_cycle_end		`integer`

OffProtocolTherapyStudy

An off-protocol therapy study record captures when and why a subject went off protocol therapy or off study.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
timings_submitter_id		`Timing`
age_off		`integer`
off_type
reason_off
another_study

SurvivalCharacteristic

A survival characteristic record captures follow-up, vital status, survival, loss to follow-up, and cause-of-death information.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
timings_submitter_id		`Timing`
age_at_lkss		`integer`
lkss
lkss_with_disease
age_lost_to_follow_up		`integer`
cause_of_death
cause_of_death_other		`string`
TRM_type
cause_of_death_detail
cause_of_death_ranking

FamilyMedicalHistory

A family medical history record captures relevant familial cancer or medical history for a subject.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
family_history
relative
prior_cancer		`string`

MedicalHistory

A medical history record captures prior or concurrent medical conditions and related history relevant to the subject.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
medical_history
medical_history_status
medical_history_category
assisted_conception

Testing

Testing contains laboratory, pathology, genomic, functional, anthropometric, and specimen-related observations used to characterize subjects, disease biology, eligibility, monitoring, and research sample availability.

Vital

A vital record captures vital sign measurements and related quantitative or categorical results.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
timings_submitter_id		`Timing`
age_at_vitals		`integer`
vitals_test
vitals_result		`string`
vitals_result_numeric		`decimal`
vitals_result_unit

FunctionTest

A function test record captures functional assessments, test categories, and associated results.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
timings_submitter_id		`Timing`
age_at		`integer`
function_category
function_result		`string`
function_test
function_result_numeric		`decimal`
function_result_unit

Lab

A lab record captures laboratory assessments, specimen context, methods, and qualitative or quantitative laboratory results.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
timings_submitter_id		`Timing`
age_at_lab		`integer`
lab_cat
lab_test
lab_spec_type
lab_seq_method
lab_result		`string`
lab_result_numeric		`decimal`
lab_result_unit
lab_method
traumatic_tap
pmid_ref		`string`
threshold_high		`decimal`
threshold_low		`decimal`

MolecularAnalysis

A molecular analysis record captures cytogenetic, genomic, and molecular findings, including tested abnormalities, genes, variants, and related results.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
timings_submitter_id		`Timing`
age_at_molecular_analysis		`integer`
molecular_analysis_method
iscn		`string`
indepen_abb		`decimal`
num_metaphases		`decimal`
molecular_abnormality
chromosome		`string`
gene1		`string`
gene2		`string`
variant_type
genetic_seq		`string`
aa_mutation		`string`
molecular_abnormality_result
allelic_ratio		`decimal`
anaplasia
anaplasia_extent
copy_number_status
cytodifferentiation
dna_index
dna_index_numeric		`decimal`
karyotype_status
mitoses
num_chromosomes		`decimal`

Biospecimen

A biospecimen record describes available biological specimens and associated storage, media, type, and quantity information.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
biospecimen_container_type		`string`
biospecimen_media		`string`
biospecimen_type		`string`
current_qty_unit		`string`
current_qty_value		`string`

Immunohistochemistry

An immunohistochemistry record captures IHC assessments, tested markers, and reported results.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
timings_submitter_id		`Timing`
age_at_ihc		`integer`
ihc_test
ihc_result		`string`
ihc_result_numeric		`decimal`

Cytology

A cytology record captures cytologic assessments, specimen context, and the presence or absence of malignant cells.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
timings_submitter_id		`Timing`
age_at_cytology		`integer`
malignant_cells
cytology_spec_type

Imaging

An imaging record captures imaging assessments, modalities, results, and disease-specific imaging scores.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
timings_submitter_id		`Timing`
age_at_imaging		`integer`
imaging_method
imaging_result
deauville_score
qpet_score		`decimal`

Disease Attributes

Disease Attributes contains diagnostic, staging, anatomic, histologic, biologic, risk, extent-of-disease, and disease-site concepts used to characterize the subject's cancer or cancer-related condition.

Histology

A histology record captures pathologic and morphologic tumor findings, including histology, grade, morphology codes, and related results.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
timings_submitter_id		`Timing`
age_at_hist_assessment		`integer`
hist_assessment_review
histology
histology_result		`string`
histology_result_numeric		`decimal`
histology_result_unit
hist_ICD_O_morph_code		`string`
histology_grade
mature_glial_implants
somatic_malignancy_type
histology_inpc

Staging

A staging record captures disease stage and staging-system information used to classify disease extent.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
timings_submitter_id		`Timing`
age_at_staging		`integer`
AB
E
S
stage_system
stage
irs_group
tnm_finding

DiseaseCharacteristic

A disease characteristic record captures disease-defining clinical features, risk factors, disease sites, symptoms, and classification variables.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
timings_submitter_id		`Timing`
fab_type
who_aml
disease_site
detection_method
CNS_disease_status
MPAL
MLDS
TAMDS
secondary_AML
bulky_nodal_aggregate
BULK_MED_MASS
bulk_disease
fever
igccc_risk_group
initial_treatment_category
karnofsky
lansky
magic_risk_group
med_ratio		`decimal`
mki
night_sweats
nodular_splenic
weight_loss
histology_inpc

MyeloidSarcomaInvolvement

A myeloid sarcoma involvement record captures the presence and site of myeloid sarcoma involvement.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
timings_submitter_id		`Timing`
myeloid_sarcoma
myeloid_sarcoma_site

TumorAssessment

A tumor assessment record captures tumor-level characteristics such as site, classification, laterality, size, invasion, nodal involvement, and related findings.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
timings_submitter_id		`Timing`
age_at_tumor_assessment		`integer`
necrosis
necrosis_pct		`decimal`
nodal_site
tumor_detection_method
tumor_classification
tumor_site
tumor_laterality
tumor_state
nodal_involvement
depth
invasiveness
longest_diam_dim1		`decimal`
longest_diam_dim2		`decimal`
longest_diam_dim3		`decimal`
nodal_clinical
nodal_pathology
parameningeal_extension
pleural_effusion
tumor_site_other		`string`
tumor_size

LesionCharacteristic

A lesion characteristic record captures lesion-level disease findings, including lesion site, classification, measurements, effusions, and lesion response.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
timings_submitter_id		`Timing`
age_at_lesion_assessment		`integer`
lesion_assessment_review
lesion_detection_method
lesion_classification
lesion_site
e_extension_site
lesion_laterality
lesion_bulky
longest_diam_dim1		`decimal`
diam_dim1_type
longest_diam_dim2		`decimal`
diam_dim2_type
longest_diam_dim3		`decimal`
diam_dim3_type
pleural_effusion
pericardial_effusion
lesion_response
lesion_pct_change		`decimal`

Intervention

Intervention contains treatment and procedure records, including surgery, medications, radiation therapy, transplantation, transfusion, cellular therapy, locoregional therapy, fertility preservation procedures, and protocol treatment modifications.

BiopsySurgicalProcedure

A biopsy or surgical procedure record captures procedure timing, site, type, extent, margins, and related tumor specimen findings.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
timings_submitter_id		`Timing`
age_at_procedure		`integer`
procedure_performed
procedure_treatment_timing
procedure_site
procedure_laterality
procedure_type
procedure_extent
mass_present
viable_tumor_specimen
viable_tumor_margin
margins
tumor_classification

StemCellTransplant

A stem cell transplant record captures transplant type, source, donor relationship, HLA matching, conditioning, and related transplant details.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
timings_submitter_id		`Timing`
age_at_sct		`integer`
sct_type
sct_source
sct_donor_relationship
hla_match
number_hla		`decimal`
number_matches		`decimal`
hla_a_result
hla_b_result
hla_c_result
hla_drb1_result
hla_dq_result
sct_conditioning_type
sct_tbi
sct_cd34_coll		`decimal`

TransfusionMedicineProcedure

A transfusion medicine procedure record captures transfusion-related procedures, products, timing, and unit information.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
timings_submitter_id		`Timing`
age_at_tmp_start		`integer`
tmp_type
tmp_product
tmp_product_type
tmp_number_units		`decimal`

RadiationTherapy

A radiation therapy record captures radiation treatment timing, site, dose, laterality, boost, energy type, and fractionation details.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
timings_submitter_id		`Timing`
age_at_rt_start		`integer`
age_at_rt_end		`integer`
rt_timing
administration_status
rt_site
rt_dose		`decimal`
rt_unit
boost_dose		`decimal`
boost
energy_type
num_fraction		`decimal`
rt_laterality
tumor_classification

TotalDose

A total dose record summarizes administered or intended systemic therapy dose over a defined treatment interval.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
timings_submitter_id		`Timing`
age_at_total_dose_start		`integer`
age_at_total_dose_end		`integer`
cycle_number		`integer`
administration_status
route
antineoplastic_agent
number_doses		`decimal`
total_dose_administered		`decimal`
total_dose_intended		`decimal`
total_dose_units
route_detail

ProtocolTreatmentModifications

A protocol treatment modification record captures modifications to protocol therapy, including rationale, reason, toxicity details, and agent substitutions.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
timings_submitter_id		`Timing`
age_at_mod		`integer`
mod_type
mod_rationale
mod_reason
toxicity_detail
toxicity_immune
toxicity_infusion
original_agent
sub_agent

CellularImmunotherapy

A cellular immunotherapy record captures cellular immunotherapy timing and treatment type.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
timings_submitter_id		`Timing`
age_at_cimt_start		`integer`
cimt_type

NonProtocolTherapy

A non-protocol therapy record captures therapy given outside protocol treatment, including timing and therapy type.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
npt_timing
npt_type
npt_sct_type

Monitoring

Monitoring contains response, residual disease, toxicity, late effects, subsequent neoplasms, reproductive outcomes, patient-reported outcomes, and other follow-up concepts used to evaluate disease course and treatment impact over time.

SubjectResponse

A subject response record captures disease response assessments, response criteria, methods, and response-related laboratory or clinical findings.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
timings_submitter_id		`Timing`
age_at_response		`integer`
response_method
response_category
response_criteria
response_criteria_version		`string`
response
bm_pct_blasts_at_response		`decimal`
bm_analysis_method_at_response
anc_at_response		`decimal`
anc_threshold_at_response
platelet_count_at_response		`decimal`
platelet_threshold_at_response
interim_response
necrosis
necrosis_pct		`decimal`
nodular_splenic
palpable_nodes
symptoms
tx_prior_response

MinimalResidualDisease

A minimal residual disease record captures MRD assessments, methods, sample sources, results, sensitivity, and molecular markers.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
timings_submitter_id		`Timing`
age_at_mrd_assessment		`integer`
mrd_method
flow_cytometry_type
mrd_result		`string`
mrd_result_numeric		`decimal`
mrd_result_unit
mrd_sensitivity		`decimal`
mrd_sample_source
mrd_molecular_markers

SecondaryMalignantNeoplasm

A secondary malignant neoplasm record captures subsequent malignancy occurrence, type, morphology, site, and related classification details.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
timings_submitter_id		`Timing`
age_at_smn		`integer`
smn_morph_sno		`string`
smn_morph_txt		`string`
smn_site
smn_top_sno		`string`
smn_top_txt		`string`
smn_type
smn_yn
smn_morph_icdo		`string`
smn_top_icdo		`string`
smn_field

AdverseEvent

An adverse event record captures treatment- or disease-related adverse events, severity, attribution, outcome, interventions, pathogens, and GVHD-related details.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
timings_submitter_id		`Timing`
age_at_ae		`integer`
age_at_ae_resolved		`enum`
adverse_event
ae_code		`string`
ae_system
ae_system_version		`string`
ae_grade
ae_attribution
ae_outcome
ae_icu
ae_medication
ae_intervention
ae_med_intervention_detail
ae_pathogen
ae_pathogen_confirmation
gvhd_acuity
gvhd_organ

GrowingTeratomaSyndrome

A growing teratoma syndrome record captures the timing and treatment of growing teratoma syndrome.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
timings_submitter_id		`Timing`
age_at_gts		`integer`
gts_treatment

LateEffects

A late effects record captures late effects, severity, details, and CTCAE version information.

Diagram

Slot	Description	Range
subjects_submitter_id		`Subject`
age_at_le_eval		`integer`
le
le_detail
le_sub_detail
le_severity_grade
le_ctcae_version		`string`

Permissible Value	Description	Meaning
Ann Arbor A Symptoms Indicator		ncit:C185483
Ann Arbor B Symptoms Indicator		ncit:C177585
Unknown		ncit:C17998
Not Reported		ncit:C43234

AdverseEventEnum

Permissible Value	Description	Meaning
Allergic Reaction		ncit:C114476
Cardiac Toxicity		ncit:C27994
Endocrine Toxicity		ncit:C138163
Fatigue		ncit:C3036
GI Toxicity		ncit:C185646
Graft Versus Host Disease		ncit:C3063
Hemorrhage		ncit:C26791
Hepatic Toxicity		ncit:C185645
Hyperbilirubinemia		ncit:C27088
Infection		ncit:C128320
Left Ventricular Systolic Dysfunction		ncit:C64251
Mucositis		ncit:C115965
Multi Organ Failure		ncit:C75568
Musculoskeletal Toxicity		ncit:C185647
Neuropathy		ncit:C4731
Neurotoxicity Syndrome		ncit:C27961
Neutropenia		ncit:C80520
Ototoxicity		ncit:C66929
Psychiatric Toxicity		ncit:C185648
Pulmonary Toxicity		ncit:C177374
Rashes		ncit:C39594
Renal Toxicity		ncit:C115459
Sinusoidal Obstruction Syndrome		ncit:C26793
Thrombocytopenia		ncit:C3408
Typhlitis		ncit:C38043
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

AeAttributionEnum

Permissible Value	Description	Meaning
Definite		ncit:C53260
Possible		ncit:C53258
Probable		ncit:C41357
Unlikely		ncit:C53257
Unrelated		ncit:C53256
Unknown		ncit:C17998
Not Reported		ncit:C43234

Permissible Value	Description	Meaning
Expected		ncit:C41333
Unexpected		ncit:C41334

Permissible Value	Description	Meaning
Grade 1		ncit:C41338
Grade 2		ncit:C41339
Grade 3		ncit:C41340
Grade 4		ncit:C41337
Grade 5		ncit:C48275
Unknown		ncit:C17998
Not Reported		ncit:C43234

AeMedInterventionDetailEnum

Permissible Value	Description	Meaning
ACE-Inhibitor		ncit:C247
Heart Transplant		ncit:C15246
Inotropic Support		ncit:C168966
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

AeOutcomeEnum

Permissible Value	Description	Meaning
Death, Contributory		ncit:C168948
Death, Noncontributory		ncit:C173315
Not Recovered		ncit:C49494
Not Yet Recovered		ncit:C49494
Recovered		ncit:C85257
Recovered With Sequelae		ncit:C49495
Recovered with Sequelae		ncit:C49495
Unknown		ncit:C17998
Not Reported		ncit:C43234

Permissible Value	Description	Meaning
Confirmed		ncit:C25458
Suspected		ncit:C71458
Unknown		ncit:C17998
Not Reported		ncit:C43234

AePathogenEnum

Permissible Value	Description	Meaning
Bacteria	(hl) ConsortiumNote: Note: If multiple pathogens involved, include one observation per pathogen.	ncit:C14187
Fungus		ncit:C14209
Virus		ncit:C14283
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

Permissible Value	Description	Meaning
Confirmed		ncit:C25458
Suspected		ncit:C71458

AeSystemEnum

Permissible Value	Description	Meaning
Balis Neuropathy Scale		ncit:C178081
CTCAE		ncit:C49704
European Society for Blood and Marrow Transplantation (EBMT)		ncit:C168842
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

AntineoplasticAgentEnum

Permissible Value	Description	Meaning
Amifostine		ncit:C488
Amsacrine		ncit:C240
Arsenic Trioxide		ncit:C1005
Bendamustine		ncit:C73261
Bleomycin		ncit:C313
Bortezomib		ncit:C1851
Brentuximab Vedotin		ncit:C66944
Busulfan		ncit:C321
Carboplatin		ncit:C1282
Carmustine		ncit:C349
Cisplatin		ncit:C376
Cladribine		ncit:C1336
Clofarabine		ncit:C26638
Cyclophosphamide		ncit:C405
Cytarabine		ncit:C408
Dacarbazine		ncit:C411
Dactinomycin		ncit:C412
Daunorubicin		ncit:C62091
Daunorubicin (Liposomal)		ncit:C2213
Daunorubicin and Cytarabine (Liposomal)		ncit:C67504
Dexamethasone		ncit:C422
Doxorubicin		ncit:C456
Etopophos		ncit:C1093
Etoposide		ncit:C491
Etoposide Phosphate		ncit:C1093
Fludarabine		ncit:C1094
Gemcitabine		ncit:C66876
Gemtuzumab Ozogamicin		ncit:C1806
Gilteritinib		ncit:C116722
Hydrocortisone Sodium Succinate		ncit:C1819
Idarubicin		ncit:C562
Ifosfamide		ncit:C564
Melphalan		ncit:C633
Methotrexate		ncit:C642
Midostaurin		ncit:C1872
Mitoxantrone		ncit:C62050
Nitrogen Mustard		ncit:C62056
Nivolumab		ncit:C68814
Paclitaxel		ncit:C1411
Pembroluzimab		ncit:C106432
Prednisone		ncit:C770
Procarbazine		ncit:C62072
Quizartinib		ncit:C68936
Sorafenib		ncit:C61948
Thiotepa		ncit:C875
Tretinoin		ncit:C900
Venoreline		ncit:C1275
Vinblastine		ncit:C930
Vincristine		ncit:C933
Other		ncit:C17649

AssistedConceptionEnum

Permissible Value	Description	Meaning
In Vitro Fertilization		ncit:C16580
Intracytoplasmic Sperm Injection		ncit:C185482
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

CauseOfDeathDetailEnum

Permissible Value	Description	Meaning
Acute Respiratory Distress Syndrome
Bacterial Infection		ncit:C2890
Cardiac Disease		ncit:C3079
Cardiac Failure		ncit:C50577
Fungal Infection		ncit:C3245
Graft Versus Host Disease		ncit:C3063
Hemorrhage	(hl) ConsortiumNote: Note: If multiple cause of death details, include one observation per cause of death detail.	ncit:C26791
Infection, NOS		ncit:C128320
Multi Organ Failure
Organ Failure, NOS		ncit:C185320
Pulmonary Disease		ncit:C3198
Sinusoidal Obstruction Syndrome		ncit:C26793
Surgical Complication		ncit:C164157
Unacceptable Toxicity
Viral Infection		ncit:C3439
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

CauseOfDeathEnum

Permissible Value	Description	Meaning
Disease Progression	(gct) ConsortiumNote: Note: If multiple causes of death, include one observation per cause of death. (hl) ConsortiumNote: Note: If multiple causes of death, include one observation per cause of death. (nrsts) ConsortiumNote: Note: If multiple causes of death, include one observation per cause of death. There can only be one record where CAUSE_OF_DEATH_RANKING=Primary. (rms) ConsortiumNote: Note: If multiple causes of death, include one observation per cause of death. However, only one cause of death can have the varaiable CAUSE_OF_DEATH_RANKING=Primary.	ncit:C168970
Post-Treatment Disease Complications		ncit:C168877
Pre-Treatment Disease Complications		ncit:C168876
Secondary Malignancy		ncit:C4968
Treatment-Related Mortality		ncit:C166165
Treatment-Related mortality		ncit:C166165
Unrelated to Disease or Treatment		ncit:C17649
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

CimtTypeEnum

Permissible Value	Description	Meaning
Chimeric Antigen Receptor T-cell Therapy		ncit:C126102
Donor Lymphocyte Infusion		ncit:C16145
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

CourseEnum

Permissible Value	Description	Meaning
Chemoimmunotherapy		ncit:C94251
Chemotherapy	(aml) ConsortiumNote: Use this value for chemo that is not otherwise specified.	ncit:C15632
Consolidation		ncit:C15679
Immunotherapy		ncit:C15262
Induction		ncit:C158876
Intensification		ncit:C173105
Maintenance		ncit:C15688
Palliative Treatment		ncit:C15292
Prephase		ncit:C168826
Radiation Therapy		ncit:C15313
Stem Cell Transplant Conditioning		ncit:C168794
Other		ncit:C17649

DataContributorIdEnum

Permissible Value	Description	Meaning
AIEOP		ncit:C168887
BFM-SG		ncit:C168888
CCLG	(gct) ConsortiumNote: Children’s Cancer and Leukaemia Group	ncit:C177327
COG		ncit:C39353
DCOG		ncit:C168889
DFCI		ncit:C177330
GPLP
GPOH
JACLS		ncit:C168890
JCCG
JPLSG		ncit:C168891
MRC		ncit:C168892
NOPHO		ncit:C168893
NRG-Oncology		ncit:C177331
PPLLSG		ncit:C168894
SFCE	(gct) ConsortiumNote: Société Française de Lutte contre les Cancers et Leucémies de l'Enfant et de l'Adolescent	ncit:C177328
SIOPEN
SJCRH		ncit:C39510
SOPOBE	(gct) ConsortiumNote: Brazilian Society of Pediatric Oncology	ncit:C177329

DetectionMethodEnum

Permissible Value	Description	Meaning
Biopsy	(hl) ConsortiumNote: Note: If there were multiple detection methods, include one observation per detection method.	ncit:C15189
Bone Marrow Results		ncit:C190021
Cerebrospinal Fluid Results		ncit:C168884
Clinical Signs or Symptoms		ncit:C100104
Imaging		ncit:C15189
Tumor Marker	(gct) ConsortiumNote: Note: If there were multiple detection methods, include one observation per detection method.	ncit:C17220
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

DiseasePhaseEnum

Permissible Value	Description	Meaning
Initial Diagnosis	(gct) ConsortiumNote: Note: Disease phase could be 'Initial Diagnosis' phase, 'Relapse' phase, etc... (gct) ConsortiumNote: Note: Only fill in Disease Phase, Disease Phase Number, Course, and Course Number if 'AGE_' not known Note: Disease Phase could be 'Initial Diagnosis' phase, or a 'Relapse' phase, etc... (hl) ConsortiumNote: Note: Disease phase could be 'Initial Diagnosis' phase, a 'Relapse' phase, etc... (nrsts) ConsortiumNote: Note: Disease phase could be 'Initial Diagnosis' phase, 'Relapse' phase, etc... (rms) ConsortiumNote: Note: Only fill in Disease phase, Disease phase number, Course, and Course number if 'AGE_' not known Note: Disease phase could be 'Initial Diagnosis' phase, or a 'Relapse' phase, etc...	ncit:C156813
Progression		ncit:C17747
Refractory		ncit:C38014
Relapse		ncit:C38155
Relapse/Progression		ncit:C174991

EExtensionSiteEnum

Permissible Value	Description	Meaning
Bone		ncit:C12366
Chest Wall	(hl) ConsortiumNote: Note: If there were multiple extension sites, include one observation per extension site. Note: Extension sites are tied to the LESION_SITE variable. If an extension site is present, but the original site from which it originated is unclear or unknown, LESION_SITE should be marked as 'unknown.'	ncit:C62484
Heart		ncit:C12727
Lungs		ncit:C12468
Soft Tissue		ncit:C12471
Other		ncit:C17649

EnergyTypeEnum

Permissible Value	Description	Meaning
3D Conformal		ncit:C16035
Brachytherapy		ncit:C15195
Electrons
Intensity-Modulated Radiation Therapy		ncit:C16135
Photon		ncit:C88112
Proton		ncit:C66897
Protons		ncit:C66897
Other
Unknown		ncit:C17998
Not Reported		ncit:C43234

FabTypeEnum

Permissible Value	Description	Meaning
AML, NOS		ncit:C27753
M0		ncit:C8460
M1		ncit:C3249
M2		ncit:C3250
M3		ncit:C3182
M3 Variant	(aml) ConsortiumNote: It is the acute promyelocytic leukemia variant as defined by Bennet et al. (FAB classification), M3 is APL (PML-RARA fusion, or other RARA fusions)	ncit:C27757
M4		ncit:C7463
M4eo		ncit:C9020
M5		ncit:C4861
M6		ncit:C8923
M7		ncit:C3170
Unknown		ncit:C17998
Not Reported		ncit:C43234

FunctionCategoryEnum

Permissible Value	Description	Meaning
Echocardiogram	(hl) ConsortiumNote: Note: Only fill in Disease Phase, Disease Phase Number, Course, and Course Number if 'AGE_' not known Note: Disease Phase could be 'Initial Diagnosis' phase, or a 'Relapse' phase, etc...	ncit:C156813
EKG		ncit:C38155
Pulmonary Function Test		ncit:C38081

FunctionResultMeasurementEnum

Permissible Value	Description	Meaning
DLCO		ncit:C38083
Ejection Fraction		ncit:C99524
FEF at 25-75%		ncit:C119546
FEV1		ncit:C38084
FVC		ncit:C111361
QTc		ncit:C100391
Shortening Fraction		ncit:C38020
Total lung capacity		ncit:C111325

FunctionResultUnitEnum

Permissible Value	Description	Meaning
%	(hl) ConsortiumNote: Note: Only fill in this variable if a numeric result is provided in ECHO_RESULT_NUMERIC.	ncit:C48570
mL		ncit:C28254
Unknown		ncit:C17998
Not Reported		ncit:C43234

GvhdOrganEnum

Permissible Value	Description	Meaning
Gastrointestinal Tract		ncit:C34082
Liver		ncit:C12392
Lung		ncit:C12468
Skin		ncit:C12470
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

HistologyEnum

Permissible Value	Description	Meaning
Adult fibrosarcoma		icdo:8810/3
Alveolar rhabdomyosarcoma (ARMS)	(rms) ConsortiumNote: Note: If multiple histological findings, include one observation per histological finding.
Alveolar soft-part sarcoma		icdo:9581/3
Angiomatoid fibrous histiocytoma		icdo:8836/1
Angiosarcoma of soft tissue		icdo:9120/3
Atypical fibromyxanthoma		icdo:8830/1
Atypical lipomatous tumour	(nrsts) ConsortiumNote: Note: If multiple histological findings, include one observation per histological finding.	icdo:8850/1
Botryoid rhabdomyosarcoma (BRMS)
Choriocarcinoma		ncit:C2948
Clear cell sarcoma of soft tissue		icdo:9044/3
Composite haemangioendothelioma		icdo:9136/1
Dedifferentiated liposarcoma		icdo:8858/3
Dermatofibrosarcoma protuberans		icdo:8832/1
Desmoid-type fibromatosis		icdo:8821/1
Desmoplastic small round cell tumour		icdo:8806/3
Dysgerminoma		ncit:C2996
Ectomesenchymoma		icdo:8921/3
Embryonal Carcinoma		ncit:C3752
Embryonal rhabdomyosarcoma (ERMS)
Epithelioid haemangioendothelioma		icdo:9133/3
Epithelioid malignant peripheral nerve sheath tumor		icdo:9542/3
Epithelioid sarcoma		icdo:8804/3
Extra-renal rhabdoid tumor		icdo:8963/3
Extraskeletal mesenchymal chondrosarcoma		icdo:9240/3
Extraskeletal myxoid chondrosarcoma		icdo:9231/3
Extraskeletal osteosarcoma		icdo:9180/3
Fibrosarcomatous dermatofibrosarcoma protuberans		icdo:8832/3
Ganglioneuroblastoma, Intermixed (Schwannian Stroma-Rich)
Ganglioneuroblastoma, Nodular (Composite)
Ganglioneuroma (Schwannian Stroma-Dominant), Maturing Subtype
Gastrointestinal stromal tumour, malignant		icdo:8936/3
Gastrointestinal stromal tumour, uncertain malignant potential		icdo:8936/1
Germinoma		ncit:C3753
Giant cell fibroblastoma		icdo:8834/1
Giant cell tumour of soft tissues		icdo:9251/1
Glomangiomatosis		icdo:8711/1
Glomus tumour (and variants)		icdo:8711/0
Gonadoblastoma		ncit:C3754
Haemosiderotic fibrolipomatous tumour		icdo:8811/1
Hodgkin Lymphoma, Classical, NOS
Hodgkin Lymphoma, Lymphocyte Depletion, NOS		ncit:C9283
Hodgkin Lymphoma, Lymphocyte-Rich		ncit:C6913
Hodgkin Lymphoma, Mixed Cellularity, NOS		ncit:C3517
Hodgkin Lymphoma, Nodular Lymphocyte Predominance		ncit:C7258
Hodgkin Lymphoma, Nodular Sclerosis, NOS		ncit:C3518
Hodgkin Lymphoma, NOS		ncit:C9357
Immature Teratoma		ncit:C4286
Infantile fibrosarcoma		icdo:8814/3
Inflammatory myofibroblastic tumour		icdo:8825/1
Intimal sarcoma		icdo:9137/3
Kaposi sarcoma		icdo:9140/3
Kaposiform haemangioendothelioma		icdo:9130/1
Leiomyosarcoma (excluding skin)		icdo:8890/3
Lipofibromatosis		icdo:8851/1
Liposarcoma, not otherwise specified		icdo:8850/3
Low-grade fibromyxoid sarcoma		icdo:8840/3
Low-grade myofibroblastic sarcoma		icdo:8825/3
Malignant glomus tumour		icdo:8711/3
Malignant granular cell tumour		icdo:9580/3
Malignant peripheral nerve sheath tumor		icdo:9540/3
Malignant Teratoma		ncit:C4287
Malignant Triton tumour		icdo:9561/3
Mature Teratoma		ncit:C9015
Mixed Germ Cell Tumor		ncit:C4290
Mixed tumour NOS		icdo:8940/0
Mixed tumour NOS, malignant		icdo:8940/3
Myoepithelioma		icdo:8982/0
Myoepithelioma carcinoma		icdo:8982/3
Myxofibrosarcoma		icdo:8811/3
Myxoid liposarcoma		icdo:8852/3
Myxoinflammatory fibroblastic sarcoma/Atypical myxoinflammatory fibroblastic tumour		icdo:8811/1
Necrotic Tumor		ncit:C36029
Neuroblastoma (Schwannian Stroma-Poor)
Ossifying fibromyxoid tumour		icdo:8842/0
Ossifying fibromyxoid tumour, malignant		icdo:8842/3
Palmar/plantar fibromatosis		icdo:8813/1
Papillary intralymphatic angioendothelioma		icdo:9135/1
PEComa NOS, benign		icdo:8714/0
PEComa NOS, malignant		icdo:8714/3
Phosphaturic mesenchymal tumour, benign		icdo:8990/0
Phosphaturic mesenchymal tumour, malignant		icdo:8990/3
Pigmented dermatofibrosarcoma protuberans		icdo:8833/1
Pleomorphic liposarcoma		icdo:8854/3
Pleomorphic rhabdomyosarcoma (PRMS)
Plexiform fibrohistiocytic tumour		icdo:8835/1
Pseudomyogenic (epithelioid sarcoma-like) haemangioendothelioma		icdo:9136/1
Retiform haemangioendothelioma		icdo:9136/1
Rhabdomyosarcoma (RMS), inadequate tissue for classification
Rhabdomyosarcoma (RMS), not classifiable
Rhabdomyosarcoma (RMS), with Mixed Embryonal and Alveolar Features
Sclerosing epithelioid fibrosarcoma		icdo:8840/3
Seminoma		ncit:C9309
Seminoma/Dysgerminoma/Germinoma	(gct) ConsortiumNote: Note: If multiple histology assessments, include one observation per histological finding.	ncit:C121618
Soft tissue chondroma		icdo:9220/0
Solitary fibrous tumour		icdo:8815/1
Solitary fibrous tumour, malignant		icdo:8815/3
Somatic Malignancy		ncit:C4289
Spindle cell
Synovial sarcoma NOS		icdo:9040/3
Synovial sarcoma, biphasic		icdo:9043/3
Synovial sarcoma, spindle cell		icdo:9041/3
Tenosynovial giant cell tumour diffuse type		icdo:9252/1
Tenosynovial giant cell tumour localized type		icdo:9252/0
Tenosynovial giant cell tumour malignant		icdo:9252/3
Teratoma, Not Otherwise Specified		ncit:C3403
Undifferentiated epithelioid sarcoma		icdo:8804/3
Undifferentiated pleomorphic sarcoma		icdo:8802/3
Undifferentiated round cell sarcoma		icdo:8803/3
Undifferentiated sarcoma NOS		icdo:8805/3
Undifferentiated spindle cell sarcoma		icdo:8801/3
Well differentiated liposarcoma		icdo:8850/3
Yolk Sac Tumor		ncit:C3011
Other
Unknown		ncit:C17998
Not Reported		ncit:C43234

HistologyGradeEnum

Permissible Value	Description	Meaning
Differentiating
FNCLCC Sarcoma Grade 1
FNCLCC Sarcoma Grade 2
FNCLCC Sarcoma Grade 3
FNCLCC Sarcoma Grade GX	(nrsts) ConsortiumNote: grade cannot be assessed
Grade 1	(gct) ConsortiumNote: Note: Only associated with Mature Teratoma.	ncit:C28077
Grade 2		ncit:C28078
Grade 3		ncit:C28079
Undifferentiated or Poorly Differentiated
Unknown		ncit:C17998
Not Reported		ncit:C43234

HlaBResultEnum

Permissible Value	Description	Meaning
Both Alleles Matched		ncit:C168821
One Allele Mismatched		ncit:C168819
Two Alleles Mismatched		ncit:C168820
Unknown		ncit:C17998
Not Reported		ncit:C43234

HlaCResultEnum

Permissible Value	Description	Meaning
Both Alleles Matched		ncit:C168821
One Allele Mismatched		ncit:C168819
Two Alleles Mismatched		ncit:C168820
Unknown		ncit:C17998
Not Reported		ncit:C43234

HlaDqResultEnum

Permissible Value	Description	Meaning
Both Alleles Matched		ncit:C168821
One Allele Mismatched		ncit:C168819
Two Alleles Mismatched		ncit:C168820
Unknown		ncit:C17998
Not Reported		ncit:C43234

HlaDrb1ResultEnum

Permissible Value	Description	Meaning
Both Alleles Matched		ncit:C168821
One Allele Mismatched		ncit:C168819
Two Alleles Mismatched		ncit:C168820
Unknown		ncit:C17998
Not Reported		ncit:C43234

HlaResultEnum

Permissible Value	Description	Meaning
Both alleles matched		ncit:C168821
One allele mismatched		ncit:C168819
Two alleles mismatched		ncit:C168820
Unknown		ncit:C17998
Not Reported		ncit:C43234

ImagingMethodEnum

Permissible Value	Description	Meaning
Bone Scan		ncit:C17646
CT		ncit:C17204
Gallium		ncit:C66798
MRI		ncit:C16809
PET		ncit:C17007
PET-CT		ncit:C103512
PET-MRI		ncit:C103514
Ultrasound		ncit:C64384
X-Ray		ncit:C38101

InitialTreatmentCategoryEnum

Permissible Value	Description	Meaning
Conventional-dose chemotherapy (2-8 cycles) plus surgery
Intensive multi-modality therapy: no stem cell or bone marrow transplant
Intensive multi-modality therapy: plus stem cell or bone marrow transplant
Intensive multi-modality therapy: plus stem cell or bone marrow transplant and anti-GD2 antibody
Intensive multi-modality therapy: specific type unknown
None (observation)
Surgery alone
Unknown

IrsGroupEnum

Permissible Value	Description	Meaning
Group I	(rms) ConsortiumNote: Note: Tied to AGE_AT_STAGING.
Group II, NOS
Group IIA
Group IIB
Group IIC
Group III
Group IV
Unknown
Not Reported

KarnofskyEnum

Permissible Value	Description	Meaning
0		ncit:C105720
10		ncit:C105718
100		ncit:C105707
20		ncit:C105716
30		ncit:C105715
40		ncit:C105714
50		ncit:C105713
60		ncit:C105712
70		ncit:C105711
80		ncit:C105710
90		ncit:C105709

LabCatEnum

Permissible Value	Description	Meaning
Bone Marrow Analysis		ncit:C173273
Cerebrospinal Fluid Analysis		ncit:C173272
microRNA Sequencing
Peripheral Blood Analysis		ncit:C173271
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

LabMethodEnum

Permissible Value	Description	Meaning
Cytology		ncit:C16491
ddPCR		ncit:C166064
Flow Cytometry		ncit:C16585
MicroRNA Sequencing		ncit:C156057
Morphology		ncit:C35867
Not reported		ncit:C43234
PCR		ncit:C17003
qPCR		ncit:C51962
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

LabResultUnitEnum

Permissible Value	Description	Meaning
%		ncit:C48570
count/mm3		ncit:C173275
g/dL		ncit:C64783
IU/L		ncit:C67376
mcg/mL		ncit:C64572
mg/L		ncit:C64572
mm/h		ncit:C67419
ng/mL		ncit:C67306
U/L		ncit:C67456
uIU/mL		ncit:C67405
Unknown		ncit:C17998
Not Reported		ncit:C43234

LabSpecTypeEnum

Permissible Value	Description	Meaning
Blood		ncit:C17610
Bone Marrow		ncit:C12431
Cerebrospinal Fluid		ncit:C12692
Not reported		ncit:C43234
Peritoneal Fluid
Plasma
Serum		ncit:C178987
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

LabTestEnum

Permissible Value	Description	Meaning
AFP		ncit:C21577
Albumin		ncit:C64431
Alkaline Phophatase		ncit:C64432
Auer Rods		ncit:C74657
Blasts		ncit:C74605
CD34		ncit:C102260
cfDNA		ncit:C128274
CRP		ncit:C64548
EBV DNA		ncit:C166035
EBV IgG		ncit:C184675
Eosinophils		ncit:C64550
ESR		ncit:C74611
Ferritin
Free T4		ncit:C74786
Hemoglobin		ncit:C64848
LDH		ncit:C64855
Lymphocytes		ncit:C12535
miR-367-3p		ncit:C177302
miR-371a-3p		ncit:C158711
miR-372-3p		ncit:C82190
miR-373-3p		ncit:C82191
miR-375-3p		ncit:C101665
Monocytes		ncit:C64823
Myelocyte
Neutrophils		ncit:C51949
Phosphorus
Platelets		ncit:C51951
Protein Total
RBC		ncit:C51946
Segmented Neutrophils (segs)
Total T4
TSH		ncit:C64813
Uric Acid
WBC		ncit:C51948
β-hCG		ncit:C64851

LanskyEnum

Permissible Value	Description	Meaning
0		ncit:C70538
10		ncit:C70539
100		ncit:C69426
20		ncit:C70540
30		ncit:C70541
40		ncit:C70542
50		ncit:C69421
60		ncit:C69422
70		ncit:C69423
80		ncit:C69424
90		ncit:C69425

LeDetailEnum

Permissible Value	Description	Meaning
Acquired Immunodeficiency		ncit:C2851
Arrhythmia		ncit:C2881
Arthritis		ncit:C2883
Atrophy		ncit:C79748
Autoimmune Reaction		ncit:C16313
Avascular-Necrosis		ncit:C118385
Bladder Disorder		ncit:C2900
Conduction Abnormality		ncit:C78245
Contraction		ncit:C30085
Dryness		ncit:C25489
Esophagitis		ncit:C9224
Gastritis		ncit:C26780
GI Adhesions		ncit:C185688
Gonadal Dysfunction		ncit:C26786
Hepatic Dysfunction		ncit:C50634
Hypertension		ncit:C3117
Musculoskeletal Hypoplasia		ncit:C185696
Neurocognitive Functions		ncit:C94321
Neuropathy		ncit:C4731
Obstructive Lung Disease		ncit:C3199
Osteopenia		ncit:C50910
Osteoporosis		ncit:C3298
Pancreatitis		ncit:C3306
Pericarditis		ncit:C34915
Pigment Changes		ncit:C124224
Reactive Airway Disease		ncit:C113673
Renal Disorder		ncit:C3149
Restrictive Lung Disease		ncit:C91762
Scarring		ncit:C34483
Scoliosis		ncit:C78603
Stroke		ncit:C3390
Telangiectasia		ncit:C28194
Thyroid Disorder	(hl) ConsortiumNote: Note: If multiple late effect details, include one observation per late effect detail.	ncit:C26893
Valvular Disease		ncit:C45525
Vascular Disorder		ncit:C35117
Ventricular Dysfunction		ncit:C111655
Other		ncit:C17649

LeEnum

Permissible Value	Description	Meaning
Breast Hypoplasia		ncit:C78222
Cardiovascular Disorder		ncit:C2931
Dermatologic Disorder		ncit:C3371
Endocrine Disorder	(hl) ConsortiumNote: Note: If multiple late effects, include one observation per late effect.	ncit:C3009
Fatigue		ncit:C3036
Genitourinary Disorder		ncit:C156660
GI Disorder		ncit:C2990
Immunologic Disorder		ncit:C3507
Musculoskeletal Disorder		ncit:C107377
Neurological Disorder		ncit:C26835
Psychiatric Disorder		ncit:C2893
Pulmonary Disorder		ncit:C3198
Xerostomia		ncit:C26917

LeSubDetailEnum

Permissible Value	Description	Meaning
AIN		ncit:C176730
AKI		ncit:C26808
Amenorrhea		ncit:C61443
Asthma		ncit:C28397
Cardiomyopathy, NOS		ncit:C34830
Decreased Creatinine Clearance		ncit:C185671
Decreased GFR		ncit:C78326
Dilated Cardiomyopathy		ncit:C84673
Fertility Disorder		ncit:C3836
Germ Cell Failure, Confirmed		ncit:C185685
Germ Cell Failure, Suspected		ncit:C185684
Heart Block		ncit:C50501
Hyperthyroid	(hl) ConsortiumNote: Note: If multiple late effect sub-details, include one observation per late effect sub-detail.	ncit:C3123
Hypothyroid		ncit:C26800
Menstrual Cycle Dysfunction		ncit:C34815
Motor Neuropathy		ncit:C3500
Prolonged QT		ncit:C71034
Pulmonary Fibrosis		ncit:C26869
Restrictive Cardiomyopathy		ncit:C62798
Sensory Neuropathy		ncit:C3501
Supraventricular Tachycardia		ncit:C35061
Testosterone Deficiency		ncit:C143195
Thyroid Nodule		ncit:C3415
Tubular Damage		ncit:C185689
Other		ncit:C17649

LesionDetectionMethodEnum

Permissible Value	Description	Meaning
Biopsy		ncit:C15189
Bone Scan		ncit:C17646
CT Scan		ncit:C17204
Gallium Scan		ncit:C38087
Lymphangiogram		ncit:C16805
MRI		ncit:C16809
PET Scan		ncit:C17007
PET-CT		ncit:C103512
PET-MRI		ncit:C103514
Physical Examination		ncit:C20989
Staging Laparotomy		ncit:C15266
Ultrasound		ncit:C64384
X-Ray		ncit:C38101
Other		ncit:C17649

LesionResponseEnum

Permissible Value	Description	Meaning
Complete Response		ncit:C4870
Complete Response Unconfirmed		ncit:C165198
Partial Response		ncit:C18058
Progressive Disease		ncit:C35571
Stable Disease		ncit:C18213

LesionSiteEnum

Permissible Value	Description	Meaning
Axilla or Pectoral
Axillary Nodes		ncit:C12904
Bone		ncit:C12366
Bone Marrow		ncit:C12431
Celiac Nodes		ncit:C65166
Cervical Nodes	(hl) ConsortiumNote: Note: If there were multiple lesions, include one observation per lesion (hl) ConsortiumNote: Note: These sites only refer to primary or metastatic lesions, not to sites of extension (see below). If LESION_TYPE is primary, only chose cervical nodes - popliteal notes, bone, or unknown. If LESION_TYPE is metastatic, only choose Bone - Liver, or other	ncit:C32298
Epitrochlear Nodes		ncit:C98182
Hilar Nodes		ncit:C33600
Iliac
Iliac Crest		ncit:C32765
Infraclavicular Lymph Node		ncit:C63705
Inguinal Nodes		ncit:C32801
Inguinal or Femoral
Liver		ncit:C12392
Lung		ncit:C12468
Mediastinum		ncit:C6634
Mesenteric Nodes		ncit:C77641
Muscle
Paraaortic Lymph Node		ncit:C77643
Pectoral Nodes		ncit:C120322
Pleura
Popliteal Nodes		ncit:C53146
Preauricular Lymph Node		ncit:C103429
Skin
Spleen		ncit:C7295
Splenic Hilar Nodes		ncit:C33600
Supraclavicular Lymph Node		ncit:C12903
Thyroid
Waldeyer's Ring		ncit:C73468
Unknown		ncit:C17998
Not Reported		ncit:C43234

MarginsEnum

Permissible Value	Description	Meaning
Biopsy Only
Incomplete Resection
R0 - Complete Resection, Negative Margins		ncit:C139578
R1 - Complete Resection, Positive Margins		ncit:C139579
R2 - Gross Residual Disease		ncit:C139580
Unknown		ncit:C17998

MedicalHistoryCategoryEnum

Permissible Value	Description	Meaning
Autoimmune Disease		ncit:C2889
Congenital Anomaly		ncit:C2849
Genetic Syndrome		ncit:C3101
Unknown		ncit:C17998
Not Reported		ncit:C43234

MedicalHistoryEnum

Permissible Value	Description	Meaning
APC
Beckwith-Wiedemann Syndrome		ncit:C34415
Celiac Disease		ncit:C26714
Central Hypoventilation Syndrome		ncit:C98889
Cleft Lip		ncit:C87175
Cleft Palate		ncit:C87069
Clubfoot		ncit:C84641
Costello
Costello Syndrome		ncit:C84652
Cushing Syndrome		ncit:C2969
Denys-Drash Syndrome		ncit:C84668
Diabetes Mellitus (Type I)		ncit:C2986
DICER1
Down Syndrome		ncit:C2993
Frasier Syndrome		ncit:C122805
Gastroschisis		ncit:C84725
Gonadal Dysgenesis		ncit:C61420
Goodpasture's Syndrome		ncit:C34649
Gorlin Syndrome		ncit:C2892
Graves' Disease		ncit:C3071
Hashimoto's Thyroiditis		ncit:C27191
Heart Defect		ncit:C168217
Hemihypertrophy		ncit:C88541
Hereditary Retinoblastoma		ncit:C8495
Hirschsprung Disease		ncit:C34700
Inflammatory Bowel Disease		ncit:C3138
Juvenile Idiopathic Arthritis		ncit:C114357
Klinefelter Syndrome		ncit:C34752
Li-Fraumeni
Li-Fraumeni Syndrome		ncit:C3476
Lynch Syndrome		ncit:C8494
Mixed Connective Tissue Disease		ncit:C84892
Multiple Sclerosis		ncit:C3243
Neurofibromatosis Type I		ncit:C143014
NF-1
Noonan Syndrome		ncit:C34854
Psoriasis		ncit:C3346
RB1
Scleroderma		ncit:C26746
Secondary Malignancy
Swyer Syndrome		ncit:C85178
Systemic Lupus Erythematosus		ncit:C3201
Trisomy 21		ncit:C43224
Trisomy 21 Mosaicism		ncit:C142099
Turner Syndrome	(gct) ConsortiumNote: Note: If subject had multiple medical history conditions, include one observation per condition.	ncit:C26900
Vitiligo		ncit:C26915
WAGR Syndrome		ncit:C3718
Werner Syndrome		ncit:C3447
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

ModReasonEnum

Permissible Value	Description	Meaning
Drug Not Available		ncit:C185643
Hematologic Toxicity	(hl) ConsortiumNote: Note: If multiple reasons for modififcation, include one observation per reason.	ncit:C15474
Non-Hematologic Toxicity		ncit:C185641
Pre-Existing Organ Dysfunction		ncit:C185644
Scheduling Issues		ncit:C185642
Subject Non-Compliance		ncit:C91752
Surgical Complications		ncit:C164157
Other		ncit:C17649

ModTypeEnum

Permissible Value	Description	Meaning
Delayed		ncit:C25476
Discontinued		ncit:C25484
Dose Reduction	(hl) ConsortiumNote: Note: If multiple modifications made, include one observation per modification.	ncit:C49505
New Agent Addition		ncit:C185633
Not Given		ncit:C106487
Substitution		ncit:C54071
Other		ncit:C17649

MolecularAbnormalityEnum

Permissible Value	Description	Meaning
11q deletion
16q loss
17q gain
17q Gain
1p deletion
45XO	(gct) ConsortiumNote: Note: If multiple molecular abnormalities, include one observation per molecular abnormality.	ncit:C26900
45XO w/ Y Chromosomal Material		ncit:C176781
46XX		ncit:C120197
46XY		ncit:C120198
47XXX		ncit:C129718
47XXY		ncit:C34752
47XYY		ncit:C85237
48XXXX		ncit:C176787
48XXXY		ncit:C89799
8q gain
ALK Amplification
ALK Copy Number Gain
ALK Copy Number Loss
ALK Mutation
ALK Rearranged
ALK Rearrangement
ASPSCR1-TFE3
BCOR ITT Rearranged
BCOR-CCNB3
Biallelic CEBPA Gene Mutation		ncit:C157569
CEBPA Gene Mutation		ncit:C38372
CEBPA mutation - mutation unspecified
CIC-DUX4
CKIT mutation - ex17		ncit:C116396
CKIT mutation - ex8		ncit:C128660
CKIT mutation - unspecified	(aml) ConsortiumNote: t(9;11)(p21.3;q23.3)	ncit:C39712
del(13q)		ncit:C36497
del(13q)(13q 14 - 21)		ncit:C168770
del(17p)		ncit:C36499
del(5q)(5q31-q32)		ncit:C168769
der.12p		ncit:C173542
ETV6 rearranged
ETV6 Rearranged
ETV6-MN1 Fusion		ncit:C99678
EWSR1 Rearranged
EWSR1-ATF1
EWSR1-CREB1
EWSR1-ETV1/4
EWSR1-PBX1/ZNF44/POU5F1
FLT3 D835N Pathogenic Variant
FLT3 internal tandem duplication (ITD)		ncit:C67494
FLT3-TKD	(aml) ConsortiumNote: t(6;9)(p23;q34.1)	ncit:C67495
FOXO1 Rearranged	(nrsts) ConsortiumNote: Note: If multiple molecular abnormalities, include one observation per molecular abnormality.
FUS-CREB3L2
GATA1 mutation		ncit:C82340
iAMP21
inv(16)(p13.3q24.3)/CBFA2T3-GLIS2		ncit:C167195
inv(16)(p13q22)		ncit:C36373
inv(3)(q21.3;q26.2)	(aml) ConsortiumNote: t(v;11q23.3)	ncit:C36407
inv(3)(q21;q21.2)
K-RAS mutation	(aml) ConsortiumNote: t(11;17)(q23;q12-21)	ncit:C41361
Loss of Chromosome 11q (Deletion)
Loss of Chromosome 1p (Deletion)
MLL Other partner	(aml) ConsortiumNote: t(8;16)(p11.2;p13.3)	ncit:C36517
MLL rearrangement		ncit:C122623
MLL-MLLT10(AF10) Fusion
MLL-MLLT3 Fusion
Monoallelic CEBPA Gene Mutation		ncit:C168774
Monosomy 5		ncit:C36523
Monosomy 7	(aml) ConsortiumNote: split	ncit:C36411
MYCN Amplification
N-RAS mutation	(aml) ConsortiumNote: split	ncit:C41381
Non-KMT2A MLLT10		ncit:C168771
None detected
NPM1 mutation		ncit:C168774
NTRK Rearranged
Other-FOXO1
p.F1174L
p.R1275L
PAX3-FOXO1	(rms) ConsortiumNote: Note: If multiple molecular abnormalities, include one observation per molecular abnormality.
PAX3-Other
PAX7-FOXO1
PML-RARA Fusion	(aml) ConsortiumNote: t(9;22)(q34.1;q11.2)
PTPN11 mutation		ncit:C82612
ROS1 Rearranged
RUNX1 mutation	(aml) ConsortiumNote: GATA2/MECOM Fusion Gene	ncit:C38362
RUNX1-RUNX1T1 Fusion		ncit:C99294
SMARCB1 Deleted/Mutated
SSX-SS18
t(10;11)(p11.2;q23)		ncit:C168758
t(10;11)(p12;q23) / MLL-MLLT10(AF10)	(aml) ConsortiumNote: t(1;22)(p13.3;q13.1)	ncit:C132102
t(11;15)(p15;q35)/NUP98/JARID1A		ncit:C131505
t(11;17)(AF17)		ncit:C168760
t(11;19)(q23;p13) (MLL-ENL)/(MLL-ELL)		ncit:C168764
t(11;19)(q23;p13.1) (MLL-ELL)	(aml) ConsortiumNote: KMT2A Gene Rearrangement	ncit:C36371
t(11;19)(q23;p13.3) (MLL-ENL)		ncit:C36372
t(15;17)(q24;q21)		ncit:C27758
t(16;16)(p13.1;q22)		ncit:C27759
t(16;21)(p11;q22)FUS/ERG		ncit:C36616
t(16;21)(q24;q22)RUNX1-CBFA2T3		ncit:C168773
t(1;11)(q21;q23) / MLL-MLLT11(AF1Q)		ncit:C168759
t(1;22)(RBM15-MKL1)		ncit:C36417
t(2;12)		ncit:C173543
t(3;12)(q23;p12.3) / ETV6/EVI1		ncit:C168766
t(3;3)(q21;q26.2), RPN1-EVI1		ncit:C36406
t(3;5)(q25;q34)NPM1/MLF1		ncit:C36415
t(4;11)(q21;q23) / MLL-MLLT2(AF4)		ncit:C36365
t(5;11)(q35;p15) NSD1/NUP98		ncit:C131503
t(6;11)(q27;q23) / MLL-MLLT4(AF6)		ncit:C36610
t(6;9)(p23;q34) (DEK/NUP214)		ncit:C36532
t(7;12)(q36;p13) HLXB9(MNX1)/ETV6(TEL)		ncit:C122689
t(8;16)MOZ/CBP		ncit:C167194
t(8;21)(q22;q22) RUNX1/ETO
t(9;11)(p22;q23) / MLL-MLLT3(AF9)		ncit:C36370
t(9;22)(q34;q11.2) ABL/BCR		ncit:C13271
t(v;q23,3); KMT2A
TCF3-PBX1 Fusion		ncit:C99291
TGFBR3-MGEA5
TP53 mutation
Trisomy 10
Trisomy 21		ncit:C43224
Trisomy 3		ncit:C36425
Trisomy 4
Trisomy 8		ncit:C36396
VGLLA2 Rearranged
Wild Type		ncit:C62195
WT1 mutation		ncit:C146726
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

MolecularAnalysisMethodEnum

Permissible Value	Description	Meaning
Capillary Electropheresis		ncit:C17637
Cytogenetics		ncit:C16487
Fluorescence In Situ Hybridization		ncit:C17563
Gel Electropheresis		ncit:C18091
Karyotype		ncit:C16768
Karyotyping		ncit:C16768
Next Generation Sequencing		ncit:C101293
Reverse Transcriptase-Polymerase Chain Reaction		ncit:C18136
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

MrdMethodEnum

Permissible Value	Description	Meaning
Flow Cytometry		ncit:C16585
Molecular Real-Time Quantitative PCR		ncit:C51962
Next Generation Sequencing		ncit:C101293
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

MrdMolecularMarkersEnum

Permissible Value	Description	Meaning
Any MLL rearrangement		ncit:C122623
Biallelic CEBPA Gene Mutation		ncit:C157569
CEBPA Gene Mutation		ncit:C38372
CKIT Mutation - Ex17		ncit:C116396
CKIT Mutation - Ex8		ncit:C128660
CKIT Mutation - Unspecified	(aml) ConsortiumNote: t(9;11)(p21.3;q23.3)	ncit:C39712
del(13q) (13q 14 - 21)		ncit:C168770
del(17p)		ncit:C36499
del(5q)(5q31-q32)		ncit:C168769
der.12p		ncit:C173542
FLT3 internal tandem duplication		ncit:C67494
FLT3-TKD	(aml) ConsortiumNote: t(6;9)(p23;q34.1)	ncit:C67495
GATA1 Mutation		ncit:C82340
inv(16)(p13.3q24.3) / CBFA2T3-GLIS2		ncit:C167195
inv(16)(p13q22) (G2704-G2759)
inv(3)(q21.3;q26.2)	(aml) ConsortiumNote: t(v;11q23.3)	ncit:C36407
K-RAS Mutation	(aml) ConsortiumNote: t(11;17)(q23;q12-21)	ncit:C41361
MLL Other Partner	(aml) ConsortiumNote: t(8;16)(p11.2;p13.3)	ncit:C36517
Monoallelic CEBPA Gene Mutation		ncit:C168774
Monosomy 5		ncit:C36523
Monosomy 7	(aml) ConsortiumNote: split	ncit:C36411
N-RAS Mutation	(aml) ConsortiumNote: split	ncit:C41381
Non-KMT2A MLLT10		ncit:C168771
NPM1 mutation		ncit:C82429
PTPN11 Mutation	(aml) ConsortiumNote: t(9;22)(q34.1;q11.2)	ncit:C82612
RUNX1 mutation	(aml) ConsortiumNote: GATA2/MECOM Fusion Gene	ncit:C38362
RUNX1-RUNXT1 Fusion
t(10;11)(p11.2;q23)	(aml) ConsortiumNote: t(1;22)(p13.3;q13.1)	ncit:C168758
t(10;11)(p12;q23) / MLL-MLLT10(AF10)		ncit:C132102
t(11;15)(p15;q35) / NUP98/JARID1A		ncit:C131505
t(11;17)(AF17)	(aml) ConsortiumNote: KMT2A Gene Rearrangement	ncit:C168760
t(11;19)(q23;p13) (MLL-ENL)/(MLL-ELL)		ncit:C168764
t(11;19)(q23;p13.1) (MLL-ELL)		ncit:C36371
t(11;19)(q23;p13.3) (MLL-ENL)		ncit:C36372
t(15;17)(q24;q21)		ncit:C27758
t(16;16)(p13.1;q22)		ncit:C27759
t(16;21)(p11;q22) / FUS/ERG		ncit:C36616
t(16;21)(q24;q22) / RUNX1-CBFA2T3		ncit:C168773
t(1;11)(q21;q23) / MLL-MLLT11(AF1Q)		ncit:C168759
t(1;22)(RBM15-MKL1)		ncit:C36417
t(2;12)		ncit:C173543
t(3;12)(q23;p12.3)(ETV6/EVI1)		ncit:C168766
t(3;3)(q21;q26.2)		ncit:C36406
t(3;5)(q25;q34)NPM1/MLF1		ncit:C36415
t(3;5)(q25;q34)NPM1/MLF2
t(3;5)(q25;q34)NPM1/MLF3
t(4;11)(q21;q23) / MLL-MLLT2(AF4)		ncit:C36365
t(5;11)(q35;p15) NSD1/NUP98		ncit:C131503
t(6;11)(q27;q23) / MLL-MLLT4(AF6)		ncit:C36610
t(6;9)(p23;q34) DEK/NUP214		ncit:C36532
t(7;12)(q36;p13) HLXB9(MNX1)/ETV6(TEL)		ncit:C122689
t(8;16)MOZ/CBP		ncit:C167194
t(8;21)		ncit:C119608
t(9;11)(p22;q23) / MLL-MLLT3(AF9)		ncit:C36370
t(9;22)(q34;q11.2) ABL/BCR		ncit:C13271
Trisomy 8		ncit:C36396
WT1 mutation		ncit:C146726
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

MyeloidSarcomaSiteEnum

Permissible Value	Description	Meaning
Bone		ncit:C12366
CNS		ncit:C12438
Orbit		ncit:C12347
Skin		ncit:C12470
Testis		ncit:C12412
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

NptTypeEnum

Permissible Value	Description	Meaning
Chemotherapy	(hl) ConsortiumNote: Note: If multiple non-protocol therapies, include one observation per therapy.	ncit:C15632
Immunotherapy		ncit:C15262
Radiation Therapy		ncit:C15313
Stem Cell Transplant		ncit:C15431
Surgery		ncit:C17173
Other		ncit:C17649

OriginalAgentEnum

Permissible Value	Description	Meaning
Bendamustine	(hl) ConsortiumNote: Note: Refers to the agent to which the modification was made, or the new agent that was added to treatment.	ncit:C73261
Bleomycin		ncit:C313
Brentuximab Vedotin		ncit:C66944
Busulfan		ncit:C321
Carboplatin		ncit:C1282
Carmustine		ncit:C349
Cisplatin		ncit:C376
Cyclophosphamide		ncit:C405
Cytarabine		ncit:C408
Dacarbazine		ncit:C411
Dexamethasone		ncit:C422
Doxorubicin		ncit:C456
Etoposide		ncit:C491
Etoposide Phosphate		ncit:C1093
Fludarabine		ncit:C1094
Gemcitabine		ncit:C66876
Ifosfamide		ncit:C564
Melphalan		ncit:C633
Methotrexate		ncit:C642
Nitrogen Mustard		ncit:C62056
Nivolumab		ncit:C68814
Pembrolizumab		ncit:C106432
Prednisone		ncit:C770
Procarbazine		ncit:C62072
Thiotepa		ncit:C875
Vinblastine		ncit:C930
Vincristine		ncit:C933
Vinorelbine		ncit:C1275
Other		ncit:C17649

ProcedureExtentEnum

Permissible Value	Description	Meaning
Complete Resection		ncit:C175027
Equivocal		ncit:C178921
Gross Total		ncit:C131672
Partial Resection		ncit:C131680
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

ProcedurePurposeEnum

Permissible Value	Description	Meaning
Biopsy of Distant Site for Staging		ncit:C185530
Diagnostic Biopsy for Possible Recurrence		ncit:C185534
Initial Diagnostic Procedure		ncit:C185527
Second Look Surgery to Attempt Total Resection		ncit:C185528
Other		ncit:C17649

ProcedureSiteEnum

Permissible Value	Description	Meaning
Abdomen
Abdominal Wall
Anal/Perianal
Axillary Nodes		ncit:C12904
Bladder
Bladder/Prostate
Bone		ncit:C12366
Bone Marrow		ncit:C12431
Bone or Bone Marrow
Brain
Brain/Leptomeninges
Breast
Celiac Nodes		ncit:C65166
Cervical Nodes	(hl) ConsortiumNote: Note: If there were surgery sites, include one observation per site	ncit:C32298
Cervix
Cheek
Chest Wall
Distant Lymph Nodes
Distant Nodes
Epitrochlear		ncit:C98182
Eyelid
Foot
Forearm
Frontal Cortex	(gct) ConsortiumNote: Frontal Lobe	ncit:C32635
Hand
Head
Head and Neck		ncit:C12418
Hilar Nodes		ncit:C134731
Hip
Hypopharynx
Iliac Crest		ncit:C32765
Infraclavicular Nodes		ncit:C63705
Infratemporal Fossa/Pterygopalatine
Infratemporal Fossa/Pterygopalatine and Parapharyngeal Area
Inguinal		ncit:C32801
Intraperitoneal
Intrathoracic
Kidney
Knee
Larynx
Leg
Liver		ncit:C12392
Liver/Biliary Tract
Lower Arm
Lower Leg
Lung		ncit:C12468
Mediastinum		ncit:C6634
Mesenteric Nodes		ncit:C77641
Middle Ear
Nasal Cavity
Nasal Cavity and Paranasal Sinuses
Nasopharynx
Neck
Occipital Cortex	(gct) ConsortiumNote: Occipital Lobe	ncit:C12757
Oral Cavity
Orbit
Oropharynx
Ovary		ncit:C12404
Para-Aortic Nodes		ncit:C77643
Paranasal Sinuses
Parapharyngeal Area
Paraspinal
Paratesticular
Parietal Cortex	(gct) ConsortiumNote: Parietal Lobe	ncit:C12766
Parotid
Pectoral Nodes		ncit:C120322
Pelvis
Perineum
Peritoneum
Pineal		ncit:C12398
Pleura
Pleural Effusion
Popliteal Nodes		ncit:C53146
Preauricular Nodes		ncit:C103429
Prostate
Retroperitoneal
Retroperitoneum		ncit:C28256
Sacrococcygeal		ncit:C33506
Scalp
Shoulder
Soft Tissue
Spinal Cord		ncit:C12464
Spleen		ncit:C7295
Splenic Hilar Nodes		ncit:C33600
Supraclavicular Nodes		ncit:C12903
Suprasellar/Neurohypophyseal		ncit:C177357
Temporal Cortex	(gct) ConsortiumNote: Temporal Lobe	ncit:C12797
Testis		ncit:C12412
Thalamus		ncit:C12459
Thigh
Thorax
Thyroid and Parathyroid
Trunk
Upper Arm
Urogenital
Uterus
Vagina		ncit:C12407
Vulva
Waldeyer's Ring		ncit:C73468
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

RaceEnum

Permissible Value	Description	Meaning
American Indian or Alaska Native		ncit:C41259
Asian		ncit:C41260
Black or African American		ncit:C16352
Multiracial		ncit:C67109
Native Hawaiian or Other Pacific Islander		ncit:C41219
White		ncit:C41261
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

ReasonOffEnum

Permissible Value	Description	Meaning
Adverse Event		ncit:C41331
Completion of Follow-Up		ncit:C178071
Completion of Planned Therapy		ncit:C168935
Death		ncit:C93546
Development of SNM		ncit:C4968
Disease Progression		ncit:C35571
Failure to Attain Remission		ncit:C178072
Ineligible		ncit:C40412
Lost to Follow-Up		ncit:C70740
Physician Decision		ncit:C48250
Relapse		ncit:C38155
Secondary Malignancy		ncit:C4968
Study Discontinuation		ncit:C142444
Subject Non-Compliance		ncit:C91752
Subject/Guardian Refused Further Treatment		ncit:C168934
Withdrawal of Consent		ncit:C48271
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

RelativeEnum

Permissible Value	Description	Meaning
Brother		ncit:C96570
Daughter		ncit:C150887
Father		ncit:C96572
Mother		ncit:C96580
Sister		ncit:C96586
Son		ncit:C150888
Other		ncit:C17649
Unknown		ncit:C17998

ResponseCategoryEnum

Permissible Value	Description	Meaning
Bone Marrow Response		ncit:C173307
Central Nervous System Response		ncit:C168952
Myeloid Sarcoma Response		ncit:C168965
Non-Target Lesions		ncit:C94535
Overall Response		ncit:C96613
Target Lesions		ncit:C94534
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

ResponseCriteriaEnum

Permissible Value	Description	Meaning
Choi		ncit:C122394
mRECIST		ncit:C126031
PERCIST		ncit:C126039
RECIST		ncit:C49164
WHO		ncit:C75419
Unknown		ncit:C17998
Not Reported		ncit:C43234

ResponseEnum

Permissible Value	Description	Meaning
Complete Response	(hl) ConsortiumNote: Note: For HL, refers to end of chemotherapy or late response.	ncit:C4870
Non-Response		ncit:C173526
Not Evaluable
Partial Response		ncit:C18058
Progressive Disease		ncit:C35571
Stable Disease		ncit:C18213
Very Good Partial Response		ncit:C123618
Unknown		ncit:C17998
Not Reported		ncit:C43234

ResponseMethodEnum

Permissible Value	Description	Meaning
Bone Marrow Biopsy		ncit:C15193
Bone Scan		ncit:C17646
CT		ncit:C17204
Gallium		ncit:C66798
Imaging		ncit:C17220
MRI		ncit:C16809
Not Applicable		ncit:C48660
Pathology		ncit:C18189
PET	(hl) ConsortiumNote: Note: If RESPONSE_CATEGORY is 'overall' and not based on a single response method, RESPONSE_METHOD should be 'Not applicable'	ncit:C17007
PET-CT		ncit:C103512
PET-MRI		ncit:C103514
Tumor Marker		ncit:C17369
Ultrasound		ncit:C64384
X-ray		ncit:C38101
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

RtSiteEnum

Permissible Value	Description	Meaning
Abdomen		ncit:C12664
Abdominal Wall
Anal/Perianal
Axilla		ncit:C12674
Axilla or Pectoral
Bladder
Bladder/Prostate
Bone
Bone Marrow
Bone or Bone Marrow
Brain
Brain/Leptomeninges
Breast
Cervix
Cheek
Chest		ncit:C25389
Chest Wall
Cranium		ncit:C12789
Distant Lymph Nodes
Distant Nodes
Eyelid
Foot
Forearm
Frontal Cortex	(gct) ConsortiumNote: Frontal Lobe	ncit:C32635
Hand
Head
Head and Neck		ncit:C12418
Heart, Pericardium
Hip
Hypopharynx
Iliac
Infratemporal Fossa/Pterygopalatine
Infratemporal Fossa/Pterygopalatine and Parapharyngeal Area
Intraperitoneal
Intrathoracic
Kidney
Knee
Larynx
Leg
Liver		ncit:C12392
Liver/Biliary Tract
Lower Arm
Lower Leg
Lung		ncit:C12468
Mediastinum		ncit:C12748
Mesenteric or Hepatis Porta
Middle Ear
Nasal Cavity
Nasal Cavity and Paranasal Sinuses
Nasopharynx
Neck		ncit:C13063
Occipital Cortex	(gct) ConsortiumNote: Occipital Lobe	ncit:C12757
Oral Cavity
Orbit
Oropharynx
Ovary		ncit:C12404
Paraaortic
Paranasal Sinuses
Parapharyngeal Area
Paraspinal
Paratesticular
Paratracheal
Parietal Cortex	(gct) ConsortiumNote: Parietal Lobe	ncit:C12766
Parotid
Pelvis		ncit:C12767
Perineum
Peritoneum
Pineal		ncit:C12398
Pleura
Pleural Effusion
Prostate
Retroperitoneal
Retroperitoneum		ncit:C28256
Sacrococcygeal		ncit:C33506
Scalp
Shoulder
Soft Tissue
Spinal Cord		ncit:C12464
Splenic Hilar or Spleen
Suprasellar/Neurohypophyseal		ncit:C177357
Temporal Cortex	(gct) ConsortiumNote: Temporal Lobe	ncit:C12797
Testes		ncit:C12412
Thalamus		ncit:C12459
Thigh
Thorax
Thyroid and Parathyroid
Trunk
Upper Arm
Urogenital
Uterus
Vagina		ncit:C12407
Vulva
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

SctConditioningTypeEnum

Permissible Value	Description	Meaning
Myeloablative		ncit:C131679
Non-Myeloablative		ncit:C62714
Reduced Intensity Conditioning/Reduced Toxicity Conditioning		ncit:C116471
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

SctDonorRelationshipEnum

Permissible Value	Description	Meaning
Biological parent		ncit:C166114
Biological relative		ncit:C71384
Biological sibling		ncit:C100809
Biologically unrelated		ncit:C130053
Unknown		ncit:C17998
Not Reported		ncit:C43234

SctSourceEnum

Permissible Value	Description	Meaning
Bone marrow		ncit:C15194
Cord blood		ncit:C15640
Mixture of Stem Cells		ncit:C168886
Peripheral blood		ncit:C15430
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

SomaticMalignancyTypeEnum

Permissible Value	Description	Meaning
Adenocarcinoma		ncit:C2852
Malignant Histiocytosis		ncit:C7202
Primitive Neuroectodermal Tumor		ncit:C3716
Rhabdomyosarcoma	(gct) ConsortiumNote: Note: Only associated with Somatic Malignancy.	ncit:C3359
Sarcoma, Not Otherwise Specified		ncit:C9118
Squamous Cell Carcinoma		ncit:C2929
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

StageEnum

Permissible Value	Description	Meaning
EVANS, Stage I		ncit:C27966
EVANS, Stage II		ncit:C28054
EVANS, Stage III		ncit:C27970
EVANS, Stage IV		ncit:C27971
EVANS, Stage IVs
INRGSS, Stage L1
INRGSS, Stage L2
INRGSS, Stage M
INRGSS, Stage MS
INSS, Stage 1
INSS, Stage 2a
INSS, Stage 2b
INSS, Stage 3
INSS, Stage 4
INSS, Stage 4s
Stage 0		ncit:C4523
Stage I	(gct) ConsortiumNote: Note: Tied to stage system.	ncit:C8071
Stage IA		ncit:C6361
Stage IB		ncit:C6362
Stage II		ncit:C8116
Stage IIA		ncit:C6364
Stage IIB		ncit:C6365
Stage IIC		ncit:C6366
Stage III		ncit:C8129
Stage IIIA		ncit:C6369
Stage IIIB		ncit:C6368
Stage IIIC		ncit:C6367
Stage IS		ncit:C6363
Stage IV		ncit:C8142
Unknown		ncit:C17998
Not Reported		ncit:C43234

StageSystemEnum

Permissible Value	Description	Meaning
AJCC		ncit:C39315
Ann Arbor		ncit:C54179
COG		ncit:C39353
FIGO	(gct) ConsortiumNote: Note: If there were multiple staging systems used, include one observation per staging system	ncit:C89808
Unknown		ncit:C17998
Not Reported		ncit:C43234

StudyIdEnum

Permissible Value	Description	Meaning
0892
0896
0901
0902
0911
0914
0924
0925
0926
0927
0931
0935
0936
0937
0961
0962
09709
099
321P1
321P2
321P3
321P4
323P
3881
3891
3951
461
4941
4941L
7942
8105
8340
8441
8605
8607
8661
8671
8741
8742
8743
8863
8970
9000
9047
9072
9075
9082
9140
9243
9244
9248
9262
9272
9275
9280
9284
9285
9340
9341
9342
9343
9346
9347
9360
9361
9372
9375
9376
9382
9464
9466
9470
9571
9572
9579
9581
9640
9670
9675
9900
9907
A0935A
A09713
A3961
A3973
AADM01P1
AALL0232
AALL0331
AALL03B1
AALL0434
AALL08B1
AAML00P2
AAML03P1		ncit:C168936
AAML0531		ncit:C168937
AAML05P1
AAML07P1
AAML1031		ncit:C168938
AB9804
ABTR01B1
ABTR04B1
ACCL0331
ACCL0423
ACCL0431
ACCL05C1
ACCL0934
ACCL0935
ACCL1031
ACCL1032
ACCL1034
ACCL15N1CD
ACCL1633
ACCL21C2
ACNS02B3
ADVL0016
ADVL0017
ADVL0018
ADVL0122
ADVL0211
ADVL0212
ADVL0214
ADVL0215
ADVL0314
ADVL0316
ADVL0413
ADVL0414
ADVL0416
ADVL0421
ADVL0516
ADVL0517
ADVL0524
ADVL0525
ADVL0612
ADVL06B1
ADVL0714
ADVL0812
ADVL0813
ADVL0816
ADVL0821
ADVL0911
ADVL0912
ADVL0916
ADVL0918
ADVL0921
ADVL1011
ADVL1013
ADVL1014
ADVL1111
ADVL1112
ADVL1115
ADVL1211
ADVL1212
ADVL1213
ADVL1312
ADVL1314
ADVL1315
ADVL1411
ADVL1412
ADVL1414
ADVL1416
ADVL1513
ADVL1522
ADVL1615
ADVL1622
AEIOPAML2002		ncit:C168942
AEPI07N1
AEWS07B1
AGCT0132		ncit:C177343
AGCT01P1		ncit:C177342
AGCT0521		ncit:C177344
AGCT1531
AHEP1531
AHOD0031		ncit:C185311
AHOD03P1		ncit:C185314
AHOD0431		ncit:C185310
AHOD0831		ncit:C185308
AHOD1221		ncit:C185313
AHOD1331		ncit:C185312
AIEOPLAM92		ncit:C173254
ALTE03N1
ALTE05N1
ALTE15N2
ALTE1621
AML-BFM Registry2012		ncit:C173251
AML-BFM Registry2017		ncit:C182031
AML-BFM1998		ncit:C182032
AML-BFM2004		ncit:C168939
AML-BFM2004 Interim
AML-BFM2012		ncit:C173250
AML-BFM2019
AML-BFM2020
AML-BFM83/87
AML-BFM87/93
AML-BFM93
AML-BFM98
AML-BFM98 Interim 2003
ANBL0032
ANBL00B1
ANBL00P1
ANBL00P2
ANBL00P3
ANBL02P1
ANBL0321
ANBL0322
ANBL0421
ANBL0531
ANBL0532
ANBL0621
ANBL0931
ANBL09P1
ANBL1021
ANBL1221
ANBL1232
ANBL12P1
ANBL1531
ANBL17P1
ANBL1821
ANBL19P1
ANBL2131
ANUR0631
ANUR1131
AOST06B1
APEC14B1
APEC1621E
APEC1621F
APEC1621H
APEC1621I
APEC1621SC
APL
AREN0321
AREN03B2
ARST0331
ARST0431
ARST0531
ARST08P1
AS942
AS972
AS9801
B003
B903
B904
B925
B947
B953
B954
B973
CWS-IV-2002
CWS2002p
CWS91
CWS96
D9501
D9602
D9802
D9803
DBAML01		ncit:C168944
E04
E15
E18
ENSG5
GC1		ncit:C177335
GC2		ncit:C177336
GOG0078
GOG0090
GOG0116		ncit:C177339
I03
JACLSAML99		ncit:C168943
JPLSGAML05		ncit:C168941
LNESG1
ML-DS-2006
MRCAML12		ncit:C168945
MRCAML15		ncit:C173252
MTS2008_RMS
N891
NB2004-HR
NB2005
NB2008
NB2012
NB84
NB8814
NB91
NB97
NOPHOAML1993
NOPHOAML2004		ncit:C168946
NOPHOAML2012		ncit:C173253
P9462
P9480
P9485
P9641
P9749		ncit:C177340
P9761
P9772
P9851
P9963
P9972
PED-CITN-02
PEPN2011
PEPN2111
POG-8844
POG9049		ncit:C177341
PPLLSGAML98		ncit:C168947
R9702
RMS2005
RMS4.99
RMS95
RMS96
S31
S901
S912
S921
SCFEELAM02		ncit:C173255
SIOPEN HR-NBL1
SIOPEN-EUNB
SJCRHAML02		ncit:C168940
St. Jude's Trials - TBD	(hl) ConsortiumNote: Add in APEC14B1?
TCGM2004
TE04		ncit:C177345
TE05		ncit:C177346
TE08		ncit:C177347
TE09		ncit:C177349
TE13		ncit:C177350
TE20		ncit:C177351
TE22		ncit:C177348
TGM85		ncit:C177332
TGM90		ncit:C177333
TGM95		ncit:C177334
TIP		ncit:C177352
X0942

SubAgentEnum

Permissible Value	Description	Meaning
Bendamustine	(hl) ConsortiumNote: Note: Refers to the agent that was substituted instead of the original agent.	ncit:C73261
Bleomycin		ncit:C313
Brentuximab Vedotin		ncit:C66944
Busulfan		ncit:C321
Carboplatin		ncit:C1282
Carmustine		ncit:C349
Cisplatin		ncit:C376
Cyclophosphamide		ncit:C405
Cytarabine		ncit:C408
Dacarbazine		ncit:C411
Dexamethasone		ncit:C422
Doxorubicin		ncit:C456
Etopophos		ncit:C1093
Etoposide		ncit:C491
Fludarabine		ncit:C1094
Gemcitabine		ncit:C66876
Ifosfamide		ncit:C564
Melphalan		ncit:C633
Methotrexate		ncit:C642
Nitrogen Mustard		ncit:C62056
Nivolumab		ncit:C68814
Pembroluzimab		ncit:C106432
Prednisone		ncit:C770
Procarbazine		ncit:C62072
Thiotepa		ncit:C875
Venoreline		ncit:C1275
Vinblastine		ncit:C930
Vincristine		ncit:C933
Other		ncit:C17649

TmpTypeEnum

Permissible Value	Description	Meaning
Exchange Transfusion		ncit:C173284
Simple Transfusion		ncit:C173285
Therapeutic Apheresis		ncit:C173286
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

TnmFindingEnum

Permissible Value	Description	Meaning
Favorable Site, M0	(rms) ConsortiumNote: Note: Tied to AGE_AT_STAGING.
Metastases, ML
Other site, any T, a, N0, M0
Other site, any T, a, N1, M0, any T, b, N0/N1, M0
Unknown
Not Reported

TotalDoseUnitsEnum

Permissible Value	Description	Meaning
IU		ncit:C48579
IU/m2		ncit:C67378
mg		ncit:C28253
mg/kg		ncit:C67401
mg/Kilo		ncit:C67401
mg/m2		ncit:C67402
Not reported		ncit:C43234
Unknown		ncit:C17998
Not Reported		ncit:C43234

ToxicityDetailEnum

Permissible Value	Description	Meaning
Allergic Reaction	(hl) ConsortiumNote: Note: If multiple toxicity details, include one observation per toxicity detail.	ncit:C114476
Cardiac Toxicity		ncit:C27994
Endocrine Toxicity		ncit:C138163
GI Toxicity		ncit:C185646
Hepatic Toxicity		ncit:C185645
Infection		ncit:C128320
Mucositis		ncit:C115965
Musculoskeletal Toxicity		ncit:C185647
Neuropathy		ncit:C4731
Neutropenia		ncit:C80520
Psychiatric Toxicity		ncit:C185648
Pulmonary Toxicity		ncit:C177374
Rashes		ncit:C39594
Renal Toxicity		ncit:C115459
Thrombocytopenia		ncit:C3408
Other		ncit:C17649

TreatmentArmEnum

Permissible Value	Description	Meaning
A
A Randomized Trial Of Clofarabine Plus Cytarabine Versus Conventional Induction Therapy And Of Natural Killer Cell Transplantation Versus Conventional Consolidation Therapy In Patients With Newly Diagnosed Acute Myeloid Leukemia
A Randomized Trial Of Clofarabine Plus Cytarabine Versus Conventional Induction Therapy And Of Natural Killer Cell Transplantation Versus Conventional Consolidation Therapy In Patients With Newly Diagnosed Acute Myeloid Leukemia, dated 04/03/08
A: No adjuvant treatment
ADxE
ADxE - AI-haM, AI- HAE - standard maintenance(Standard Risk arm)
ADxE - ATRA - ATO (HR)
ADxE- AI-haM-HAE- Standard maintenance (Standard Risk arm)
ADxE- AI-haM-HAE- Standard maintenance, 12 Gy (Standard Risk arm)
ADxE- AI/2CDA-haM-HAE- Standard maintenance, 12 Gy (Standard Risk arm)
ADxE- HAM Sorafenib, AI Sorafenib, haM Sorafenib, standard maintenance (Intermediate Risk arm)
ADxE- HAM Sorafenib, AI Sorafenib, haM Sorafenib, Stem Cell Transplantation (High Risk arm)
ADxE-AI-hAM-HAE, ATRA, 12Gy
ADxE-AI-hAM-HAE, ATRA, 18Gy
ADxE-HAM- AI-haM, HAE- Standard maintenance (High Risk arm)
ADxE-HAM- AI-haM, HAE- Standard maintenance (Intermediate Risk arm)
ADxE-HAM- AI-haM, HAE- Standard maintenance, 12 Gy (High Risk arm)
ADxE-HAM- AI-haM, HAE- Standard maintenance, 12 Gy (Standard Risk arm)
ADxE-HAM- AI-haM, HAE- Standard maintenance, 18 Gy (High Risk arm)
ADxE-HAM- AI-haM, SCT
ADxE-HAM- AI-haM, SCT (High risk arm)
ADxE-HAM- AI/2CDA-haM, HAE- Standard maintenance (High Risk arm)
ADxE-HAM- AI/2CDA-haM, HAE- Standard maintenance, 12 Gy (High Risk arm)
ADxE-HAM- AI/2CDA-haM, HAE- Standard maintenance, 18 Gy (High Risk arm)
ADxE-HAM- AI/2CDA-haM, SCT
ADxE-HAM-AI-haM, SCT (High Risk arm)
AI-ATRA-ATO (High Risk)
AIE - ATRA - ATO (HR)
AIE, AI, haM, HA, ATRA
AIE, AI, haM, HAE, 18Gy, ATRA
AIE, ATO-ATRA
AIE- AI-haM-HAE- Standard maintenance (Standard Risk arm)
AIE- AI-haM-HAE- Standard maintenance, 12 Gy (Standard Risk arm)
AIE- AI-haM-HAE- Standard maintenance, 18 Gy (Standard Risk arm)
AIE- AI/2CDA-haM-HAE- Standard maintenance, 12 Gy (Standard Risk arm)
AIE-AI-hAM-HAE, ATRA, 12Gy
AIE-AI-hAM-HAE, ATRA, 18Gy
AIE-AI-hAM-HAE- Standard maintenance (Standard Risk- inv16)
AIE-HAM- AI-haM, HAE- Standard maintenance, 12 Gy (High Risk arm)
AIE-HAM- AI-haM, HAE- Standard maintenance, 12 Gy (Standard Risk arm)
AIE-HAM- AI-haM, HAE- Standard maintenance, 18 Gy (High Risk arm)
AIE-HAM- AI-haM, SCT
AIE-HAM- AI/2CDA-haM, HAE- Standard maintenance (High Risk arm)
AIE-HAM- AI/2CDA-haM, HAE- Standard maintenance, 12 Gy (High Risk arm)
AIE-HAM- AI/2CDA-haM, HAE- Standard maintenance, 18 Gy (High Risk arm)
AIE-HAM-AI-haM-HAE- Standard maintenance (Standard Risk)
AIE-HAM-AI/2CDA-haM-HAE- Standard maintenance (Intermediate Risk)
AIE-HAM-AI/2CDA-haM-HSCT (High Risk)
AIE-HAM-AI/2CDA-haM-HSCT(High Risk)
AIE-HAM-haM, HAE- Standard maintenance, 12 Gy (High Risk arm)
AIET
AIET-AM-HAM-HAE-HA-HAE
AIET-AM-HAM-HAE-HA-SCT
AIET-AM-HAM-HAE-SCT
AIET-AM-HAM-SCT
AMD/VCR - D9602
AML BFM 2004 High Risk
AML BFM 87 High Risk
AML BFM 93 High Risk
AML BFM 98 High Risk
AML BFM 98 Standard Risk
AML2002: A Collaborative Trial for the Treatment of Patients with Newly Diagnosed Acute Myeloid Leukemia or Myelodysplasia
APL AI-ATRA-ATO (High Risk)
APL ATRA-ATO ( Standard Risk)
APL ATRA-ATO (Standard Risk)
ARM A
Arm A
Arm A DS
Arm A HR
Arm A IR
Arm A LR
ARM B
Arm B
Arm B HR
Arm B IR
Arm B LR
Arm C
Arm D
Arm E
Assigned to Regimen B
ATEDox
ATEDox-AM-HAM-HAE-HA-HAE
ATEDox-AM-HAM-HAE-HA-HAE-SCT
ATEDox-ATEDox-HAM-HAE-HA-HAE
ATEDox-ATEDox-HAM-HAE-HA-SCT
ATEDox-ATEDox-HAM-HAE-SCT
ATEDox-ATEDox-HAM-SCT
ATEDox-ATEDox-SCT
ATEDox-HA-HAM
ATEDox-HA-HAM-HAE
ATEDox-HA-HAM-HAE-HA-SCT
ATEDox-HA-HAM-SCT
ATEDox-HA-MACE
ATRA - ATO (SR)
B
B: Low risk; adjuvant radiotherapy
Baseline Treatment with 2 cycles
Baseline Treatment with 4 cycles
Baseline Treatment with 8 cycles
C
C: Intermediate and high risk patients; adjuvant chemotherapy + radiotherapy
CDxA
CDxA- AI-haM, AI- HAE - standard maintenance(Standard Risk arm)
CDxA-HAM- AI-haM- HAE -Standard maintenance (Intermediate Risk arm)
CEVAIE
cisRA
CPT-11/VAC - D9802
CWS DOK IV 2004
CWS DoK IV 2004
CWS Dok IV 2004
D
D: Intermediate and high risk patients; neoadjuvant chemo- radiotherapy
Death immiately after therapy start, received exchange transfusion
Died too early
Early death
High
HIGH-2002P
High-2002P
High-2002P/Stand-B
High-A
High-A-CWS-96
High-Andere
High-B
High-Risk patient
HR
IMC - ARST08P1
individuell
individuell Topoteca
IR
IVA
IVA+VNL/CPM
IVA/VA
IVADo
IVADo+VNL/CPM
Low
Low-2002P
LR
MEC-ADE-HA3E-FLA (low risk)
MEC-ADE-HAM-HA3E-FLA
MEC-ADE-HAM-HA3E-FLA + SCT (high risk 3)
N/A
No cisRA
No data
NON protocol patient
Non-randomized conventional chemotherapy
Non-randomly assigned Single HSCT
NON-RMS
NOT RANDOMISED
Not Randomized
Off protocol before risk stratification
Purged
R0
R1
R2
R3
RA only
RA+anti-GD2
Randomized ablative chemotherapy with BMT
Randomized conventional chemotherapy
Randomized to Regimen B
Randomized to Single HSCT
Randomized to Tandem HSCT
Regimen A
Regimen B
SR
SR: AIE, Konsolidierung, AI, HAM, HAE, 12gy
Stadium Dok IV-2002
Stadium Dok IV-2002P
Stadium Dok- IV-2004
Stadium IV
Stadium IV-
Stadium IV- ?
Stadium IV-2000
Stadium IV-2002
Stadium IV-2002-Wind
Stadium IV-2002P
Stadium IV-2002P Wind
Stadium IV-2004 Dok
Stadium IV-?
Stadium IV-Andere
Stadium IV-andere
Stadium IV-B
Stadium IV-DoK IV-20
Stadium IV-Dok IV-20
Stadium IV-High-B
Stadium IV-LT
Stadium IV-LT-CWS96
Stadium IV-SIOP
Stadium IV-ST
Stadium IV-Window
Stand.-A-2002P
Stand.-B-2002P
Standard
Standard-2002P
Standard-A
Standard-Risk patient
TEM - ARST08P1
Treatment of Patients with Newly Diagnosed Acute Myeloid Leukemia or Myelodysplasia
Unpurged
VA
VAC - ARST0531
VAC - D9802
VAC - D9803
VAC x 4, VA x 12 - ARST0331
VAC x 4, VA x 4 - ARST0331
VAC/VCR - D9602
VAC/VCT - D9803
VAC/VI - ARST0531
VAIA
Very-High-2002P
Very-high-2002P
VI/VDC/IE/VAC - ARST0431
Unknown

TrmTypeEnum

Permissible Value	Description	Meaning
Chemotherapy		ncit:C15632
Immunotherapy		ncit:C15262
Stem Cell Transplant		ncit:C15431
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

TumorClassificationEnum

Permissible Value	Description	Meaning
Primary	(nrsts) ConsortiumNote: distant sites?	ncit:C8509
Metastatic		ncit:C3261
Regional Nodes		ncit:C41844
Unknown		ncit:C17998
Not Reported		ncit:C43234

TumorDetectionMethodEnum

Permissible Value	Description	Meaning
Imaging	(gct) ConsortiumNote: Note: If there were multiple methods, include one observation per method.	ncit:C17369
PET		ncit:C17007
Unknown		ncit:C17998
Not Reported		ncit:C43234

TumorSiteEnum

Permissible Value	Description	Meaning
Abdomen	(rms) ConsortiumNote: Note: If there were multiple primary sites, include one observation per primary site.
Abdominal Wall
Adrenal Gland
Anal/Perianal
Ascitic Fluid	(gct) ConsortiumNote: Note: If there were multiple primary sites, include one observation per primary site.	ncit:C159203
Bladder
Bladder/Prostate
Bone		ncit:C12366
Bone Marrow
Brain		ncit:C12439
Brain/Leptomeninges
Breast
Central Nervous System
Cerebrospinal Fluid		ncit:C12692
Cervix
Cervix Lymph Node
Cheek
Chest Wall
Distant Lymph Nodes
Distant Nodes
Eyelid
Foot
Forearm
Frontal Cortex		ncit:C32635
Hand
Head	(nrsts) ConsortiumNote: Note: If there were multiple primary sites, include one observation per primary site.
Head and Neck		ncit:C12418
Hip
Hypopharynx
Infratemporal Fossa/Pterygopalatine
Intraperitoneal
Intrathoracic
Kidney
Knee
Larynx
Leg
Liver		ncit:C12392
Liver/Biliary Tract
Lower Arm
Lower Leg
Lung		ncit:C12468
Lymph Node
Mediastinal Lymph Node		ncit:C33073
Mediastinum		ncit:C12748
Middle Ear
Nasal Cavity
Nasopharynx
Neck
Occipital Cortex		ncit:C12757
Omentum		ncit:C33209
Omentum Lymph Node
Oral Cavity
Orbit
Oropharynx
Ovary		ncit:C12404
Paranasal Sinuses
Parapharyngeal Area
Paraspinal
Paratesticular
Parathyroid
Parietal Cortex		ncit:C12766
Parotid
Pelvic Lymph Node		ncit:C12363
Pelvis
Perineum
Peritoneum		ncit:C12770
Pineal		ncit:C12398
Pleura
Pleural Effusion
Prostate
Retroperitoneal
Retroperitoneum		ncit:C28256
Retroperitoneum Lymph Node
Sacrococcygeal		ncit:C33506
Scalp
Shoulder
Skin
Soft Tissue
Spinal Cord		ncit:C12464
Spine		ncit:C12998
Suprasellar/Neurohypophyseal		ncit:C177357
Temporal Cortex		ncit:C12797
Testis		ncit:C12412
Thalamus		ncit:C12459
Thigh
Thorax
Thyroid
Trunk
Upper Arm
Urogenital
Uterus
Vagina		ncit:C12407
Vulva
Other
Unknown		ncit:C17998
Not Reported		ncit:C43234

VariantTypeEnum

Permissible Value	Description	Meaning
Amplification		ncit:C25418
Copy Number Alteration		ncit:C40207
Deletion		ncit:C19296
Gain		ncit:C36438
Insertion		ncit:C6828
Inversion		ncit:C45589
Mutation		ncit:C45576
Rearrangement		ncit:C16611
Single Nucleotide Variant		ncit:C146674
Translocation	(gct) ConsortiumNote: Derived by PCDC	ncit:C25756
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

VitalsResultUnitEnum

Permissible Value	Description	Meaning
cm		ncit:C49668
Kg	(gct) ConsortiumNote: Note: Only fill in this variable if a numeric result is provided in VITALS_RESULT_NUMERIC.	ncit:C28252
kg/m2		ncit:C49671
m2		ncit:C42569
Unknown		ncit:C17998
Not Reported		ncit:C43234

VitalsTestEnum

Permissible Value	Description	Meaning
BMI		ncit:C16358
BSA		ncit:C25157
Height		ncit:C164634
Weight	(gct) ConsortiumNote: Note: BMI should only be what is reported on CRF, not calculated from weight and height when submitting data to the PCDC	ncit:C81328

WhoAmlEnum

Permissible Value	Description	Meaning
Acute basophilic leukemia		ncit:C3164
Acute megakaryoblastic leukemia	(aml) ConsortiumNote: M7	ncit:C3170
Acute monoblastic/monocytic leukemia		ncit:C7318
Acute myelomonocytic leukemia	(aml) ConsortiumNote: M4	ncit:C7463
Acute panmyelosis with myelofibrosis		ncit:C4344
AML (megakaryoblastic) with t(1;22)(p13.3;q13.3); RBM15-MKL1		ncit:C82427
AML with biallelic mutations of CEBPA		ncit:C129782
AML with inv(16)(p13.1q22) or t(16;16)(p13.1;q22); CBFB-MYH11		ncit:C9287
AML with inv(3)(q21.3q26.2) or t(3;3)(q21.3;q26.2); GATA2, MECOM		ncit:C82426
AML with KMT2A rearrangement
AML with maturation	(aml) ConsortiumNote: M2	ncit:C3250
AML with minimal differentiation	(aml) ConsortiumNote: M0	ncit:C8460
AML with mutated NPM1		ncit:C82431
AML with myelodysplasia-related changes		ncit:C7600
AML with t(6;9)(p23;q34.1);DEK-NUP214		ncit:C82423
AML with t(8;21)(q22;q22.1); RUNX1-RUNX1T1		ncit:C9288
AML with t(9;11)(p21.3;q23.3); KMT2A-MLLT3		ncit:C82403
AML without maturation	(aml) ConsortiumNote: M1	ncit:C3249
AML, NOS		ncit:C27753
APL with PML-RARA		ncit:C7968
Myeloid leukemia associated with Down syndrome		ncit:C43223
Myeloid proliferations related to Down syndrome		ncit:C82338
Myeloid sarcoma		ncit:C3520
Provisional entity: AML with BCR-ABL1		ncit:C129785
Provisional entity: AML with mutated RUNX1		ncit:C129786
Pure erythroid leukemia		ncit:C7467
Therapy-related myeloid neoplasms		ncit:C27912
Transient abnormal myelopoiesis (TAM)		ncit:C82339
Not Reported		ncit:C43234

Permissible Value	Description	Meaning
Administered
Medication Administered
Medication Not Administered
Not Administered
Unknown

Permissible Value	Description	Meaning
Core Needle Biopsy		ncit:C15680
Incisional Biopsy		ncit:C15386
Other		ncit:C17649

Permissible Value	Description	Meaning
Contributory		ncit:C168948
Primary		ncit:C99531
Unknown		ncit:C17998
Not Reported		ncit:C43234

Permissible Value	Description	Meaning
Subject has had one or more events
Subject is censored (i.e. has had no events(s))
Unknown
Not Reported

Permissible Value	Description	Meaning
CNS1		ncit:C116833
CNS2		ncit:C116834
CNS3		ncit:C116835
Unknown		ncit:C17998
Not Reported		ncit:C43234

Permissible Value	Description	Meaning
INRG		ncit:C192760
INSTRuCT		ncit:C192758
INTERACT		ncit:C192762
MaGIC		ncit:C192759
NODAL		ncit:C192761

Permissible Value	Description	Meaning
Score 1		ncit:C99728
Score 2		ncit:C99747
Score 3		ncit:C99748
Score 4		ncit:C99749
Score 5		ncit:C99750

Permissible Value	Description	Meaning
Cranial-Caudal		ncit:C182395
Transverse		ncit:C182199
Unknown		ncit:C17998

Permissible Value	Description	Meaning
DNA Index </= 1 (Hypodiploid, Diploid)
DNA Index >1 (Hyperdiploid)
Unknown
Not Reported

Permissible Value	Description	Meaning
Hispanic or Latino		ncit:C17459
Not Hispanic or Latino		ncit:C41222
Unknown		ncit:C17998
Not Reported		ncit:C43234

Permissible Value	Description	Meaning
Different-from-Normal		ncit:C168956
Leukemia-Associated Immunophenotypes		ncit:C168812
Unknown		ncit:C17998
Not Reported		ncit:C43234

Permissible Value	Description	Meaning
Acute		ncit:C4980
Chronic		ncit:C4981
Unknown		ncit:C17998
Not Reported		ncit:C43234

Permissible Value	Description	Meaning
Central		ncit:C16104
Institutional		ncit:C41206
Unknown		ncit:C17998
Not Reported		ncit:C43234

Permissible Value	Description	Meaning
Match		ncit:C129972
Non-Match		ncit:C126298
Unknown		ncit:C17998
Not Reported		ncit:C43234

Permissible Value	Description	Meaning
IGCCC Good		ncit:C177310
IGCCC Intermediate		ncit:C177311
IGCCC Poor		ncit:C177312
Unknown		ncit:C17998
Not Reported		ncit:C43234

Permissible Value	Description	Meaning
beta-catenin		ncit:C17478
CD20		ncit:C38896
CD30		ncit:C38906
EBER		ncit:C111618
GPC3		ncit:C88175
LMP1		ncit:C18863

Permissible Value	Description	Meaning
Progressive Disease		ncit:C35571
Rapid Early Response (Adequate)		ncit:C185658
Slow Early Response (Inadequate)		ncit:C185659

Permissible Value	Description	Meaning
Abnormal Karyotype		ncit:C168875
Normal Karyotype		ncit:C173277
Unknown		ncit:C17998
Not Reported		ncit:C43234

Permissible Value	Description	Meaning
Absolute		ncit:C45829
Relative	(gct) ConsortiumNote: Note: Specific to miRNA	ncit:C45830
Unknown		ncit:C17998
Not Reported		ncit:C43234

Permissible Value	Description	Meaning
Bilateral
Left		ncit:C160200
Midline		ncit:C162614
Right		ncit:C160199

PCDC Data Model 1.15

Person

Subject

ExternalReference

Study

Timing

OffProtocolTherapyStudy

SurvivalCharacteristic

FamilyMedicalHistory

MedicalHistory

Vital

FunctionTest

Lab

MolecularAnalysis

Biospecimen

Immunohistochemistry

Cytology

Imaging

Histology

Staging

DiseaseCharacteristic

MyeloidSarcomaInvolvement

TumorAssessment

LesionCharacteristic

BiopsySurgicalProcedure

StemCellTransplant

TransfusionMedicineProcedure

RadiationTherapy

TotalDose

ProtocolTreatmentModifications

CellularImmunotherapy

NonProtocolTherapy

SubjectResponse

MinimalResidualDisease

SecondaryMalignantNeoplasm

AdverseEvent

GrowingTeratomaSyndrome

LateEffects

AbEnum

AdministrationStatusEnum

AdverseEventEnum

AeAttributionEnum

AeExpectedEnum

AeGradeEnum

AeMedInterventionDetailEnum

AeOutcomeEnum

AePathogenConfirmationEnum

AePathogenEnum

AePathogenStatusEnum

AeSystemEnum

AnaplasiaEnum

AnaplasiaExtentEnum

AntineoplasticAgentEnum

AssistedConceptionEnum

BiopsyTypeEnum

BmAnalysisMethodAtResponseEnum

CauseOfDeathDetailEnum

CauseOfDeathEnum

CauseOfDeathRankingEnum

CensorStatusEnum

CimtTypeEnum

CnsDiseaseStatusEnum

ConsortiumEnum

CopyNumberStatusEnum

CourseEnum

CytodifferentiationEnum

CytologySpecTypeEnum

DataContributorIdEnum

DeauvilleScoreEnum

DepthEnum

DetectionMethodEnum

DiamDim1TypeEnum

DiamDim2TypeEnum

DiamDim3TypeEnum

DiseasePhaseEnum

DiseaseSiteEnum

DnaIndexEnum

EExtensionSiteEnum

EnergyTypeEnum

EnrolledStatusEnum

PCDC Data Model `1.15`

Permissible Value	Description	Meaning
Low		ncit:C177354
Poor		ncit:C177356
Standard		ncit:C177355
Unknown		ncit:C17998
Not Reported		ncit:C43234

Permissible Value	Description	Meaning
Absent		ncit:C48190
Present		ncit:C25626
Unknown		ncit:C17998
Not Reported		ncit:C43234

Permissible Value	Description	Meaning
Prevention Of Adverse Event		ncit:C185654
Stem-Cell Mobilization		ncit:C62604
Treatment For Adverse Event		ncit:C88082
Other		ncit:C17649

Permissible Value	Description	Meaning
Score 1: 0-9 Mitoses per 10 HPF
Score 2: 10-19 Mitoses per 10 HPF
Score 3: > 19 Mitoses per 10 HPF
Unknown

Permissible Value	Description	Meaning
High (>4% or >200/5,000 cells)
Intermediate (2-4% or 100 to <200/5,000 cells)
Low (<2% or <100/5,000 cells)
Unknown
Not Reported

Permissible Value	Description	Meaning
Clinical Indication		ncit:C185637
Per Protocol		ncit:C181023
Unknown		ncit:C17998

Permissible Value	Description	Meaning
Absent		ncit:C38757
Not Done		ncit:C49484
Present		ncit:C38758
Unknown		ncit:C17998
Not Reported		ncit:C43234

Permissible Value	Description	Meaning
Blood		ncit:C41067
Bone Marrow		ncit:C12431
Other		ncit:C17649
Unknown		ncit:C17998
Not Reported		ncit:C43234

Permissible Value	Description	Meaning
N0 Stage Finding
N1 Stage FInding
NX Stage Finding
Unknown
Not Reported

Permissible Value	Description	Meaning
After Study Completion		ncit:C175040
Prior to Study		ncit:C175039